Dietary Phenylalanine and Brain Function

pp 201-206

Aspartame and Behavior in Children

  • Mark L. WolraichAffiliated withDivision of Developmental Disabilities, University of Iowa

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The purpose of the present chapter is to review what actual evidence exists on the relationship between aspartame and behavior in children. Nine challenge studies employing about 10 mg/kg of aspartame found no difference in children’s behavior or cognitive performance challenged with aspartame or sugar (sucrose or fructose). One study found no effect even with a larger dose of 30 mg/kg. These studies do not support a concern that aspartame has adverse effects on the behavior of children, but they were limited because they only examined short-term effects. The effects of chronic ingestion of large doses of aspartame remains unknown.