Abstract
The topographic distribution of estradiol concentrating neurons in the hypothalamus and preoptic region—which corresponds to a large degree to known terminations of the stria terminalis—suggested an amygdaloid-hypothalamic-pituitary endocrine interrelationship (Stumpf, 1968a). This concept is supported by autoradiographic findings of estradiol target cells in the anterior lobe of the pituitary (Stumpf, 1968b) as well as reports in the literature regarding the effect of lesions and hormone implantations in the amygdala, the preoptic regions, and the hypothalamus on gonadotropin secretion (e.g., Koikegami et al., 1954; Kawakami and Sawyer, 1959; Elwers and Critchlow, 1960; Yamada and Greer, 1960; Zouhar and de Groot, 1963; Eleftheriou and Zolovick, 1966; Tindal et al., 1967). As expected, subsequent dry-autoradiographic studies of the amygdala revealed a distinct pattern of estradiol concentrating hormone-neurons in this area (Stumpf and Sar, 1969; Stumpf and Sar, 1971). However, not only in the amygdala, but also in other selective parts of the phylogenetically older periventricular brain (Stumpf, 1970b), estradiol concentrating neurons (estrogen-neurons) were observed.
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Stumpf, W.E. (1972). Estrogen, Androgen, and Glucocorticosteroid Concentrating Neurons in the Amygdala, Studied by Dry Autoradiography. In: The Neurobiology of the Amygdala. Advances in Behavioral Biology, vol 2. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-8987-7_29
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DOI: https://doi.org/10.1007/978-1-4615-8987-7_29
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