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Mineralocorticoid Biosynthetic Pathways and Hypertension

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Endocrinology of Cardiovascular Function

Part of the book series: Endocrine Updates ((ENDO,volume 1))

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Abstract

The most important mineralocorticoid produced by some fish, and most amphibians, reptiles, birds and mammals is aldosterone. Other adrenal corticosteroids with variable degree of mineralocorticoid activity are also produced in smaller amounts including deoxycorticosterone (DOC), 19-nordeoxycorticosterone (19-norDOC) and 18-hydroxydeoxycorticosterone (18-OH-DOC). Some of these steroids are intermediates in the synthesis of aldosterone, others are terminal products of adrenal steroidogenic pathways, but have unclear physiological roles.

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Authors and Affiliations

  1. Endocrine Section, Harry S. on Truman Memorial Veterans Hospital Cosmopolitan International Diabetes Center Department of Internal Medicine, University of Missouri, Columbia, MO, USA, 65201

    Celso E. Gomez-Sanchez M.D.

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  1. Celso E. Gomez-Sanchez M.D.
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Editors and Affiliations

  1. DVA Medical Center and University of California, Irvine, USA

    Ellis R. Levin M.D.

  2. City of Hope Medical Center, Duarte, California, USA

    Jerry L. Nadler M.D.

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Gomez-Sanchez, C.E. (1998). Mineralocorticoid Biosynthetic Pathways and Hypertension. In: Levin, E.R., Nadler, J.L. (eds) Endocrinology of Cardiovascular Function. Endocrine Updates, vol 1. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-5569-8_16

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  • DOI: https://doi.org/10.1007/978-1-4615-5569-8_16

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