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Assessment of Coronary Blood Flow Reserve - Techniques and Limitations

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Chest Pain with Normal Coronary Angiograms: Pathogenesis, Diagnosis and Management

Part of the book series: Developments in Cardiovascular Medicine ((DICM,volume 213))

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Abstract

Coronary blood flow reserve can be defined as the amount by which coronary blood flow increases in response to maximal arteriolar dilation induced by physical or pharmacological stimulation. Thus, the term coronary reserve can also be used to indicate the amount of arteriolar tone superimposed on minimal (anatomical) resistance. Finally, as heart work is strictly dependent on coronary flow, coronary reserve can also be equated to cardiac work reserve. In fact, coronary arteriolar tone accurately adapts blood supply to moment by moment changes in myocardial energy demand. It is generally thought that arteriolar tone restricts blood flow to the minimal level compatible with tissue demand, as documented by the broad arteriovenous oxygen extraction characteristic of the coronary circulation.

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Authors
  1. Antonio L’Abbate
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Editors and Affiliations

  1. St George’s Hospital Medical School, London, UK

    Juan Carlos Kaski MD, MRCP, FACC, FESC (BHF Sugden Reader in Clinical Cardiology and Consultant Cardiologist, Head of Coronary Artery Disease Research Group) (BHF Sugden Reader in Clinical Cardiology and Consultant Cardiologist, Head of Coronary Artery Disease Research Group)

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© 1999 Springer Science+Business Media New York

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L’Abbate, A. (1999). Assessment of Coronary Blood Flow Reserve - Techniques and Limitations. In: Kaski, J.C. (eds) Chest Pain with Normal Coronary Angiograms: Pathogenesis, Diagnosis and Management. Developments in Cardiovascular Medicine, vol 213. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-5181-2_15

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  • DOI: https://doi.org/10.1007/978-1-4615-5181-2_15

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-7360-5

  • Online ISBN: 978-1-4615-5181-2

  • eBook Packages: Springer Book Archive

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