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Taurine Protection of Lungs in Hamster Models of Oxidant Injury: A Morphologic Time Study of Paraquat and Bleomycin Treatment

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Taurine

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 315))

Abstract

The intracellular reduction of oxygen is a natural part of nutrient conversion into energy and results in the production of small amounts of short-lived intermediates of oxygen; superoxide [O2-], singlet oxygen [1O2],hydrogen peroxide [H2O2] and hydroxide radical [OH]1. Naturally occurring enzymatic “scavengers” serve as the primary protection against oxidant injury2. When the production of oxygen intermediates exceeds the scavenging and detoxifying capacity of these enzymes, then lung parenchymal cell injury results3.

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Authors and Affiliations

  1. Department of Pathology - Box 1194, Mount Sinai School of Medicine, NY, New York, 10029, USA

    Ronald E. Gordon, Richard F. Heller & Rachel F. Heller

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  1. Ronald E. Gordon
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  2. Richard F. Heller
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  3. Rachel F. Heller
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Editor information

Editors and Affiliations

  1. Texas Tech University Health Sciences Center, Lubbock, Texas, USA

    John B. Lombardini

  2. University of South Alabama School of Medicine, Mobile, Alabama, USA

    Stephen W. Schaffer

  3. Osaka University Medical School, Osaka, Japan

    Junichi Azuma

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© 1992 Springer Science+Business Media New York

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Gordon, R.E., Heller, R.F., Heller, R.F. (1992). Taurine Protection of Lungs in Hamster Models of Oxidant Injury: A Morphologic Time Study of Paraquat and Bleomycin Treatment. In: Lombardini, J.B., Schaffer, S.W., Azuma, J. (eds) Taurine. Advances in Experimental Medicine and Biology, vol 315. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-3436-5_38

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  • DOI: https://doi.org/10.1007/978-1-4615-3436-5_38

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-6520-4

  • Online ISBN: 978-1-4615-3436-5

  • eBook Packages: Springer Book Archive

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