Abstract
The clonal analysis of immune response to autologous tumors has indicated that CTLs expressing the αβ-type of TcR and able to lyse autologous neoplastic cells can be grouped in two main functional subsets on the basis of the specificity and mechanism of lymphocyte-tumor interaction (Anichini et al., 1987).
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Abbreviations
- CTL :
-
Cytotoxic T Cell;
- ICAM-1 :
-
Intercellular Adhesion Molecule-1;
- IFN-γ:
-
Interferon gamma;
- LAK :
-
Lymphokine-activated Killer Cell;
- LFA-1 :
-
Lymphocyte-function Associated Antigen-3;
- MHC :
-
Major Histocompatibility Complex;
- PBL :
-
Peripheral Blood Lymphocyte;
- TAA :
-
Tumor-associated Antigen;
- TcR :
-
T Cell Receptor;
- TIL :
-
Tumor-infiltrating Lymphocyte;
- TNF-α:
-
Tumor Necrosis Factor Alpha;
- VLA :
-
Very Late Antigen
References
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© 1993 Plenum Press, New York
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Anichini, A., Mortarini, R., Parmiani, G. (1993). Interaction of Cytotoxic T Lymphocytes with Autologous Melanoma: Role of Adhesion Molecules and β1 Integrins. In: Hemler, M.E., Mihich, E. (eds) Cell Adhesion Molecules. Pezcoller Foundation Symposia, vol 4. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-2830-2_14
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DOI: https://doi.org/10.1007/978-1-4615-2830-2_14
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