Abstract
Understanding of the processes of haematopoiesistook a major leap forward when it was shown by Till and McCullouch in the 1960’s that splenic cell from normal mice could re-instate haematopoiesis in lethally irradiated mice [1]. The concepts of a multipotent haematopoietic cell emerged from these early experiments, and led to the development of in vitro investigative tools to help identify the cell(s) responsible for initiating and maintaining haematopoiesis.
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Roberts, G.T., Sacher, R.A. (1995). Impact of Cell Culture Technology on Transfusion Medicine. In: Sibinga, C.T.S., Das, P.C., Briët, E. (eds) Hereditary Diseases and Blood Transfusion. Developments in Hematology and Immunology, vol 30. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-2017-7_13
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DOI: https://doi.org/10.1007/978-1-4615-2017-7_13
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