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Role of Prolactin in Developmental Differentiation of Hypothalamic Dopaminergic Neurons

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Prolactin

Part of the book series: Endocrine Updates ((ENDO,volume 12))

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Abstract

Among the myriad biological actions of prolactin (PRL) that have been described across vertebrate classes (see [1] and other chapters in this volume) is a stimulatory effect in the brain that is part of the principle of endocrine feedback. In neuroendocrine terminology, “short-loop” feedback refers to the effects of anterior pituitary hormones on the hypophysiotropic neurons in the hypothalamus that regulate pituitary secretion. Because the majority of hypophysiotropic hormones are stimulatory (“releasing”), short-loop feedback is classically negative. However, in the case of neurons that produce inhibitory factors, pituitary feedback is positive.

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Authors and Affiliations

  1. Tulane University, New Orleans, LA, USA

    Carol J. Phelps & David L. Hurley

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  1. Carol J. Phelps
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  2. David L. Hurley
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  1. University of Cincinnati, USA

    Nelson D. Horseman

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Phelps, C.J., Hurley, D.L. (2001). Role of Prolactin in Developmental Differentiation of Hypothalamic Dopaminergic Neurons. In: Horseman, N.D. (eds) Prolactin. Endocrine Updates, vol 12. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-1683-5_2

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  • DOI: https://doi.org/10.1007/978-1-4615-1683-5_2

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-5676-9

  • Online ISBN: 978-1-4615-1683-5

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