Abstract
Blood and marrow transplantation can be an extraordinary, life-saving treatment. Once considered a therapy of last resort, it has now become the standard treatment for a number of neoplastic and immunological disorders. There has been a logarithmic increase in the number of blood and marrow transplants (BMT) performed over the past two decades, as well as in the number of diseases for which BMT is considered (Bortin et al., 1992; Sobocinski et al., 1994). With a growing number of applications, along with technologic advances in supportive care, histocompatibility testing, conditioning regimens, and control of post-transplant complications and diseases, tens of thousands of transplants are performed worldwide each year. Data from the International Bone Marrow Transplant Registry and Autologous Blood and Marrow Transplant Registry suggest 15,000 to 20,000 blood and bone marrow transplants are performed in North America annually. Outcomes are steadily improving, with an estimated 10% increase in cure rate per decade seen over the past two decades.
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Bishop, M.M., Welsh, H., Coons, M., Wingard, J.R. (2001). Blood and Marrow Transplantation. In: Rodrigue, J.R. (eds) Biopsychosocial Perspectives on Transplantation. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-1333-9_2
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DOI: https://doi.org/10.1007/978-1-4615-1333-9_2
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