Abstract
Dietary supplements are in widespread use in the United States (Eisenberg et al., 1998). This use continues to grow as more and more people become concerned about their health care and turn to supplemental self-medication. Information on the supplement use comes from many sources but there are limited data that incorporate the reason for supplement selection and employ sampling techniques that are representative of the breadth and diversity of the United States’ population. Yet the widespread use of supplements cannot be ignored or disregarded by health care providers because choice and dose of supplements can directly impact other treatment regimes and nutrient bioavailability from food (Drew and Meyers, 1997; Ernst, 1998). This chapter will provide an overview of the history and current situation with dietary supplements in the United States including the role of the National Institutes of Health Office of Dietary Supplements. Research data on selected botanical supplements commonly used by cancer patients will be reviewed. Finally, sources of information on botanical supplements will be provided.
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References
Astin JA. Why patients use alternative medicine: results of a national study. JAMA 1998; 279:1548–53.
Bokemayer C, Fels LM, Dunn T, Voight W, Gaedeke I, Schmoll HJ, Stolte H, LentzenH. Silibimin protects against cisplatin-induced nephrotoxicity without compromising cisplatin or ifosfmide anti-tumour activity. Br J Cancer 1996; 74:2036–41.
Brevoort P. The booming U.S. botanical market: a new overview. Herbalgram 1998; 44:33–47.
Burstein HJ, Gelber S, Guadagnoli E, Weeks JC. Use of alternative medicine by women with early-stage breast cancer. N Engl J Med 1999; 340:1733–39.
Chihara G. Anti-tumor and metastasis-inhibitory activities of lentinan as an immunomodulator. Cancer Detect Prey Suppl 1987:423–43.
Chu DT, Wong WL, Mavlight GM. Immunotherapy with Chinese medicinal herbs: immune restoration of local zenogeneic graft-versus-host reaction in cancer patients by fractionated Astragalus membranacueus in vitro. J Clin Lab Immunol. 1988; 25(3):1, 19–23.
Drew AK, Myers SP. Safety issues in herbal medicine: implications for the health professions. MJA 1997; 166:538–41.
Eisenberg DM, Davis RB, Ettner SL, Appel S, Wilkey S, Rompay MV, Kessler RC. Trends in alternative medicine use in the United States, 1990–1997. JAMA 1998; 280:1569–75.
Ernst E, MD. Harmless herbs? A review of the recent literature. Am J Med. 1998; 104:170–8.
Foster S. Herbs for Your Health. Loveland, Colorado: Interweave Press, 1996.
Gallup Study of attitudes toward and usage of herbal supplements. 1995, 1996, 1997., as cited in Brevoort P. The booming U.S. botanical market: a new overview. Herbalgram 1998; 44:33–47.
Houston DK, Johnson MA, Daniel TD, Poon LW. Health and dietary characteristics of supplement users in an elderly population. International J Vit and Nutr Res 1997; 67:183–91.
Khoo KS, Ang PT. Extract of Astragalus membranaceus and Ligustrum lucidum does not prevent Cyclophosphamide-induced myelosuppression. Singapore Medical Journal 36(4); 1995:387–90.
Kleijnen J, Knipchild P. Mistletoe treatment for cancer: review of controlled trials in humans. Phytomedicine 1994; 13: 255–60.
Koplan JP, Annest JL, Layde PM, Rubin GL. Nutrient intake and supplementation in the United States (NHANES II). Am J Public Health 1986; 76:287–89.
Kovacs RE, Hajto T, Kostanska K. Improvement of DNA repair in lymphocytes of breast cancer patients treated with Viscum album extract (Iscador). Europ J Cancer 1991; 27: 1672–6.
Lau BHD, Ruckle HC, Botolazzo T, Lui PD. Chinese medicinal herbs inhibit growth of murine renal cell carcinoma. Cancer biotherapy 9(2) 1994:153–61.
Looker A, Sempos CT, Johnson C, Yetley EA. Vitamin-mineral supplement use: association with dietary intake and iron status of adults. J Am Dietetic Assn 1998; 88:808–14.
Marriott BM. Vitamin D Supplementation: A Word of Caution. Annals Int Med 1997; 127(3): 231–3.
Mehta J. Intake of antioxidants among American cardiologists. Am J Cardiol 1997; 79:1558–60.
Nutrition Businesss Journal. Consumer sales 1997.1998: Web sitehttp://www.nutritionbusiness.com
Nutrition Business Journal. 1998 Internet sales of supplements hits $40 million. I 999a:Web site http://www.nutritionbusiness.com
Nutrition Business Journal. Nutrition industry generates $25.8Bn in sales. I 999b:Web sitehttp://www.nutritionbusiness.com
Ranelli PL, Dickerson RN, White KG. Use of vitamin and mineral supplements by pharmacy students. Am J Hosp Pharm 1993; 50:674–78.
Rock CL, Newman V, Flatt SW, Faerber S, Wright FA, Pierce JP. Nutrient intakes from foods and dietary supplements in women at risk for breast cancer recurrence. Nutrition and Cancer 1997; 29: 133–9.
Shibata TSE, Asetai NKM. Growth and glycoside contents of Astragalus membranaceus (Leguminosae) cultivated in different soil groups. Natural Medicines 1996; 50(4): 296–99.
Slesinski MJ, Subar AF, Kahle LL. Dietary intake of fat, fiber and other nutrients is related to the use of vitamin and mineral supplements in the United States: The 1992 National Health Interview Survey. J Nutrition 1996; 126:3001–8.
Sleinski MJ, Subar AF, Kahle LL. Trends in use of vitamin and mineral supplements in the United States: The 1987 and 1992 National Health Interview Surveys. J Am Diet Assoc 1995; 95:921–3.
Slifman NR, Obermeyer WR, AloiBK ,Musser SM, Correll WA, Cichowicz SM, Betz JM, Love LA . Contamination of botanical dietary supplements by Digitalis lanata. N Engl J Med 1998; 339: 806–10.
Spaulding-Albright N. A review of some herbal and related products commonly used in cancer patients. J Am Diet Assoc 1997; 97(suppl2): S208–15.
Stuppner H, Sturm S, Geisen G, Zillian U, Konwalinka G. A differential sensitivity of oxindole alkaloids to normal and leukemic cell lines. Planta Med 1993; Supplement A: 583.
Tslsysuki F, Miyasaka Y, Kikuchi T, Suzuki M, Hamuro J. Improvement of erythroid toxicity by lentinan and erythorpoietin in mice treated with chemotherapeutic agents. Exp Hematol 1996; 24:416–22.
Willett W, Samson L, Bain C. Vitamin supplement use among registered nurses. Am J Clin Nutr 1981; 34:1121.
Wilt TJ, Ishani A, Stark G, MacDonaldR ,Lau J, Mulrow C. Saw palmetto extracts for treatment of benign prostatic hyperplasia. JAMA 1998; 280:1604–9.
Winters B, Grosevenor M, Chon Y, Blackburn G, Copeland T, Chlebowski R, Marsoobian V, Shapiro A, Wynder E. Dietary supplement use by breast cancer participants in the women’s intervention nutrition study (WINS). FASEBJ 1997; 11(3): A160.
Worthington-Roberts B, Breskin M. Supplementation patterns of Washington state dietitians. J Am Diet Assoc 1984; 84:795–800.
Yu ZK, Liu KJ. Studies of active constituents of Astragalus membranaceus (Fisch) Bunge. Journal of Plant Resources and Environment 1993; 2(4): 40–3.
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Marriott, B.M. (2001). The Role of Dietary Supplements in Health. In: Nutrition and Cancer Prevention. Advances in Experimental Medicine and Biology, vol 492. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-1283-7_16
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DOI: https://doi.org/10.1007/978-1-4615-1283-7_16
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