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Subcellular and Extracellular Trafficking of NAD+ and Cyclic ADP-Ribose: A New Way for Regulating Intracellular Calcium Homeostasis

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Cyclic ADP-Ribose and NAADP

Abstract

Ectobiochemistry is an emerging branch of cell biology. It investigates at a molecular level all those processes that take place at the outer surface of cells. This localization can be functionally related on one hand to the interplay of solute-transporting and of ectoenzymatic activities occurring in an individual cell (autocrine model). On the other hand, ectocellular processes mediate many mechanisms of cell-to-cell communication (paracrine model), with some cells providing signal molecules to other cells and with biorecognition and molecular interactions between extracellular agonists and membrane receptors being transduced in the sensing cells to generate specific responses.

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Authors and Affiliations

  1. Department of Experimental Medicine, Section of Biochemistry, and Center of Excellence for Biomedical Research, University of Genova, Genova, Italy

    Antonio De Flora, Lucrezia Guida, Santina Bruzzone & Elena Zocchi

  2. G. Gaslini Institute, Genova, Italy

    Luisa Franco

Authors
  1. Antonio De Flora
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  2. Lucrezia Guida
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  3. Luisa Franco
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  4. Santina Bruzzone
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  5. Elena Zocchi
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Editors and Affiliations

  1. Minneapolis, USA

    Hon Cheung Lee

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De Flora, A., Guida, L., Franco, L., Bruzzone, S., Zocchi, E. (2002). Subcellular and Extracellular Trafficking of NAD+ and Cyclic ADP-Ribose: A New Way for Regulating Intracellular Calcium Homeostasis. In: Lee, H.C. (eds) Cyclic ADP-Ribose and NAADP. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-0269-2_12

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  • DOI: https://doi.org/10.1007/978-1-4615-0269-2_12

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-4996-9

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