Abstract
For genetics researchers, the DNA from our populations is our most precious commodity. We have previously indicated that the population stratifications in South Africa are likely to be a major asset in our RDD investigations. The most recent published population statistics are from the South African (SA) Census 1996 and this revealed that there were 40.58 million people in SA (http:www.gov.za/yearbook/2001/landpeople.html), classified as follows:
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References
de Villiers, J.N.P., Hillerman, R., de Jong, G., Langenhoven, E., Rossouw, H., Marx, M., and Kotze, M., 1999, High prevalence of the Cys282Tyr HF mutation facilities an improved diagnostic service for hereditary haemochromatosis in South Africa, S. Afr. Med. J. 89:279–282.
Greenberg, J., Bartmann, L., Ramesar, R., and Beighton, P., 1993, Retinitis pigmentosa in South Africa, Clin Genet. 44:232–235.
Greenberg, J., Franz, T., Goliath, R., and Ramesar, R., 1999, A photoreceptor gene mutation in an indigenous black African family with retinitis pigmentosa identified using a rapid screening approach for common rhodopsin mutations, S. Afr. Med. J., 89:877–878.
Groenewald, J.Z., Liebenberg, J., Groenewald, I.M., and Warnich, L., 1998, Linkage disequilibrium analysis in a recently founded population: Evaluation of the variegate porphyria in Southern African Afrikaners, Am. J. Hum. Genet. 62:1254–1258.
Hendricks, D., and Parker, M. I., 2002, Esophageal cancer in Africa, IUBMB Life, 53:263–268.
McKie, A. B., McHale, J. C., Keen, T. J., Tarttelin, E. E., Goliath, R. R., Greenberg, J., Ramesar, R., Cremers, F. P. M., Hoyng, C. B., van Lith-Verhoeven, J.J.C., Mackey, D.A., Bhattacharaya, S.S., Bird, A.C., Markham, A.F., and Ingleheam, C.F., 2001, Mutations in the pre-mRNA splicing factor gene PRPC8 in autosomal dominant retinits pigmentosa, Hum. Mol. Gen. 10:1555–1562.
Oswald, A. H., Goldblatt, J., Sampson, G., Clokie, R., and Beighton, P., 1985, Retinitis pigmentosa in South Africa, S. Aft. Med. J. 68:863–866.
Yeung, K. Y., Baum, L., Chan, W.M.C., Lam, D.S.C., Kwok, A.K.H., and Pang, C.P., 2001, Molecular diagnostics for retinitis pigmentosa, Clinica Chimica Acta. 313:209–215.
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Ramesar, R. et al. (2003). Retinal Degenerative Disorders in Southern Africa: A Molecular Genetic Approach. In: LaVail, M.M., Hollyfield, J.G., Anderson, R.E. (eds) Retinal Degenerations. Advances in Experimental Medicine and Biology, vol 533. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-0067-4_5
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DOI: https://doi.org/10.1007/978-1-4615-0067-4_5
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