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LTD, Spike Timing and Somatosensory Barrel Cortex Plasticity

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Excitatory-Inhibitory Balance

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Abstract

Sensory experience produces long-lasting changes in receptive fields and sensory maps in primary sensory cortical areas1. A dominant hypothesis has been that experience-dependent plasticity is mediated in part by long-term potentiation (LTP) and long-term depression (LTD) at intracortical synapses. These phenomena are attractive as candidate mechanisms for plasticity in vivo because they instantiate Hebbian learning rules2,3, which can explain many1,4, though not all5, features of map plasticity.

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Authors and Affiliations

  1. Neurobiology Section, Division of Biological Sciences, University of California San Diego, 9500 Gilman Dr., La Jolla, CA, 92093-0357, USA

    Daniel E. Feldman, Cara B. Allen & Tansu Celikel

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  1. Daniel E. Feldman
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  2. Cara B. Allen
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  3. Tansu Celikel
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Editors and Affiliations

  1. RIKEN Brain Science Institute, Wako-shi, Japan

    Takao K. Hensch  & Michela Fagiolini  & 

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Feldman, D.E., Allen, C.B., Celikel, T. (2003). LTD, Spike Timing and Somatosensory Barrel Cortex Plasticity. In: Hensch, T.K., Fagiolini, M. (eds) Excitatory-Inhibitory Balance. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-0039-1_15

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  • DOI: https://doi.org/10.1007/978-1-4615-0039-1_15

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