Abstract
In this chapter I review my tinnitus research and its relationship to use-dependent plasticity in the form of a narrative centered on International Tinnitus Seminars (ITS) and Tinnitus Research Initiative (TRI) conferences that I attended over a time span of nearly three decades. I follow this with an examination on the impact of use-dependent plasticity on my understanding of tinnitus. Finally, I speculate about the much-needed integration of mechanism and phenotypes of tinnitus that has to occur in future research and treatment.
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References
Canlon, B., Borg, E., & Flock, A. (1988). Protection against noise trauma by pre-exposure to a low level acoustic stimulus. Hearing Research, 34, 197–200.
Dominguez, M., Becker, S., Bruce, I., & Read, H. (2006). A spiking neuron model of cortical correlates of sensorineural hearing loss: Spontaneous firing, synchrony, and tinnitus. Neural Computation, 18, 2942–2958.
Eggermont, J. J. (1984). Tinnitus: Some thoughts about its origin. Journal of Laryngology and Otology, Supplement 9, 31–37.
Eggermont, J. J. (1990). On the pathophysiology of tinnitus: A review and a peripheral model. Hearing Research, 48, 111–124.
Eggermont, J. J. (2006). Cortical tonotopic map reorganization and its implications for treatment of tinnitus. Acta Oto-laryngologica Supplementum, 556, 9–12.
Eggermont, J. J. (2012). The neuroscience of tinnitus. Oxford: Oxford University Press.
Eggermont, J. J., & Kenmochi, M. (1998). Salicylate and quinine selectively increase spontaneous firing rates in secondary auditory cortex. Hearing Research, 117, 149–160.
Eggermont, J. J., & Komiya, H. (2000). Moderate noise trauma in juvenile cats results in profound cortical topographic map changes in adulthood. Hearing Research, 142, 89–101.
Eggermont, J. J., & Roberts, L. E. (2004). The neuroscience of tinnitus. Trends in Neuroscience, 27, 676–682.
Eggermont, J. J., Zeng, F.-G., Popper, A. N., & Fay, R. R., Eds. (2012). Tinnitus. New York: Springer Science + Business Media.
Fukushima, N., White, P., & Harrison, R.V. (1990). Influence of acoustic deprivation on recovery of hair cells after acoustic trauma. Hearing Research, 50, 107–118.
Hébert, S., Canlon, B., Hasson, D., Magnusson Hasson, L.L., Westerlund, H., & Theorell T. (2012). Tinnitus severity is reduced with reduction of depressive mood—a prospective population study in Sweden. PLoS One 7(5), e37733.
Jastreboff, P. J., Brennan, J. F., Coleman, J. K., & Sasaki, C. T. (1988). Phantom auditory sensation in rats: An animal model for tinnitus. Behavioral Neuroscience, 102, 811–822.
Langers, D. M., de Kleine, E., & van Dijk, P. (2012). Tinnitus does not require macroscopic tonotopic map reorganization. Frontiers in Systems Neuroscience, 6, 2.
Noreña, A. J., & Eggermont, J. J. (2005). Enriched acoustic environment after noise trauma reduces hearing loss and prevents cortical map reorganization. Journal of Neuroscience, 25, 699–705.
Noreña, A. J., & Eggermont, J. J. (2006). Enriched acoustic environment after noise trauma abolishes neural signs of tinnitus. NeuroReport, 17, 559–563.
Noreña, A. J., Gourévitch, B., Aizawa, N., & Eggermont, J. J. (2006). Spectrally enhanced acoustic environment disrupts frequency representation in cat auditory cortex. Nature Neuroscience, 9, 932–939.
Ochi, K., & Eggermont, J. J. (1996). Effects of salicylate on neural activity in cat primary auditory cortex. Hearing Research, 95, 63–76.
Pienkowski, M., & Eggermont, J. J. (2009). Long-term, partially-reversible reorganization of frequency tuning in mature cat primary auditory cortex can be induced by passive exposure to moderate-level sounds. Hearing Research, 257, 24–40.
Pienkowski, M., & Eggermont, J. J. (2012). Reversible long-term changes in auditory processing in mature auditory cortex in the absence of hearing loss induced by passive, moderate-level sound exposure. Ear & Hearing, 33, 305–314.
Roberts, L. E., Moffat, G., Baumann, M., Ward, L. M., & Bosnyak, D. J. (2008). Residual inhibition functions overlap tinnitus spectra and the region of auditory threshold shift. Journal of the Association for Research in Otolaryngology, 9, 417–435.
Seki, S., & Eggermont, J. J. (2002). Changes in cat primary auditory cortex after minor-to-moderate pure-tone induced hearing loss. Hearing Research, 173, 172–186.
Tyler, R., Coelho, C., Tao, P., Ji, H., Noble, W., Gehringer, A., & Gogel, S. (2008). Identifying tinnitus subgroups with cluster analysis. American Journal of Audiology, 17, S176–184.
Ward, L. M., & Baumann, M. (2009). Measuring tinnitus loudness using constrained psychophysical scaling. American Journal of Audiology, 18, 119–128.
Acknowledgments
My research in tinnitus and plasticity-related topics has been funded by the Canadian Institutes of Health Research, the Natural Sciences and Engineering Research Council of Canada, the Alberta Heritage Foundation for Medical Research, and the Campbell McLaurin Chair for Hearing Deficiencies.
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Eggermont, J.J. (2014). Three Decades of Tinnitus-Related Research. In: Popper, A., Fay, R. (eds) Perspectives on Auditory Research. Springer Handbook of Auditory Research, vol 50. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-9102-6_6
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DOI: https://doi.org/10.1007/978-1-4614-9102-6_6
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