Fibrous and Fibrohistiocytic Lesions

Abstract

Tumors composed solely of fibrous and fibrohistiocytic elements are diverse and cover the entire spectrum of clinical behaviors, ranging from benign, to locally aggressive, to malignant. These lesions generally produce unmineralized collagen matrix, whereas high-grade tumors may not have any matrix. These lesions often have significant overlapping histologic features and require demographic information and radiologic correlation to reach the correct diagnosis.