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Epidemiology of Tuberculosis Immunology

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The New Paradigm of Immunity to Tuberculosis

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 783))

Abstract

Immunological impairment plays a major role in the epidemiology of TB. Globally, the most common causes of immunological impairment are malnutrition, diabetes, HIV/AIDS, aging, and smoking. With the notable exception of HIV, each factor leads to relatively mild immunological impairment in individuals. However, as these conditions affect a significant proportion of the population, they contribute substantially to the incidence of TB at a global scale. Understanding immunological impairment is central to understanding the global TB pandemic, and vital to the development of effective disease control strategies.

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Authors and Affiliations

  1. Woolcock Institute of Medical Research, University of Sydney, 431 Glebe Point Road, Glebe, NSW, 2037, Australia

    G. J. Fox

  2. Respiratory Division, Montreal Chest Institute, MUHC and McGill University, Room K1.24, 3650 St. Urbain St., Montreal, PQ, H2X 2P4, Canada

    D. Menzies

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  1. G. J. Fox
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  2. D. Menzies
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Correspondence to D. Menzies .

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  1. McGill University, Montreal, H2X 2P2, Québec, Canada

    Maziar Divangahi

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Fox, G.J., Menzies, D. (2013). Epidemiology of Tuberculosis Immunology. In: Divangahi, M. (eds) The New Paradigm of Immunity to Tuberculosis. Advances in Experimental Medicine and Biology, vol 783. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-6111-1_1

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