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Abstract

Breast cancer is the most common malignancy affecting women in the United States and the second leading cause of cancer-related deaths. According to the National Cancer Institute, approximately 200,000 women are diagnosed with breast cancer each year in the United States and 40,000 die of the disease [1]. Although the vast majority of breast cancers are diagnosed in women without known risk factors, 5–10 % of newly diagnosed cases can be traced to hereditary gene mutations that significantly increase the likelihood of developing breast and other malignancies [2].

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Correspondence to Ashley N. Hardy M.D. .

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Hardy, A.N., Tarasewicz, E., Jeruss, J.S. (2013). BRCA Mutation. In: Hansen, N. (eds) Management of the Patient at High Risk for Breast Cancer. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-5891-3_3

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  • DOI: https://doi.org/10.1007/978-1-4614-5891-3_3

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