Abstract
Lesions located within the sella and parasellar region of the brain may present with similar clinical symptoms and imaging findings. Anatomic location and key imaging characteristics can aid in the differentiation of these tumors. Major anatomic references within the sella and parasellar region include the pituitary gland, pituitary stalk, optic chiasm, hypothalamus, cavernous sinus, sphenoid sinus, and the meninges. Although the most common tumors located within this region are pituitary adenoma, it is important to consider other less common entities that will also be discussed in this chapter. Normal pituitary may vary in size with gender and age. Premenopausal women tend to have a larger pituitary gland than men and postmenopausal women. Magnetic resonance imaging (MRI) is generally the modality of choice for identification of lesions within this region. There are a few imaging pitfalls and it is important to be aware that nearly 15–20 % of lesions found within the pituitary are asymptomatic incidental findings.
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References
Johnsen DE, Woodruff WW, Allen IS, et al. MR imaging of the sellar and juxtasellar regions. Radiographics. 1991;11:727–58.
Osborne AG. Sella and pituitary. In: Mascarenaz AD, Dearth CL, Kaerli M, editors. Diagnostic imaging: brain. Salt Lake City: Amirsys; 2005. p. 4–7.
Bronstein MD, Paraiba DB, Jallad RS. Management of pituitary tumors in pregnancy. Nat Rev Endocrinol. 2011;7:301–10.
Osborne AG. Sella and pituitary. In: Mascarenaz AD, Dearth CL, Kaerli M, editors. Diagnostic imaging: brain. Salt Lake City: Amirsys; 2005. p. 20–2.
Cottier JP, Destriex C, Brunereau L, et al. Cavernous sinus invasion by pituitary adenoma: MR imaging. Radiology. 2000;215:463–9.
Osborne AG. Sella and pituitary. In: Mascarenaz AD, Dearth CL, Kaerli M, editors. Diagnostic imaging: brain. Salt Lake City: Amirsys; 2005. p. 24–6.
Berkmann S, Fandino J, Zosso S, et al. Intraoperative magnetic resonance imaging and early prognosis for vision after transsphenoidal surgery for sellar lesions. J Neurosurg. 2011;115:518–27.
Byun WB, Kim OL, Kim DS. MR imaging findings of Rathke’s cleft cysts: significance of intracystic nodules. AJNR Am J Neuroradiol. 2000;21:485–8.
Osborne AG. Sella and pituitary. In: Mascarenaz AD, Dearth CL, Kaerli M, editors. Diagnostic imaging: brain. Salt Lake City: Amirsys; 2005. p. 16–8.
Gupta DK, Ojha BK, Sarkar C, et al. Recurrence in craniopharyngiomas: analysis of clinical and histological features. J Clin Neurosci. 2006;13:438–42.
Osborne AG. Sella and pituitary. In: Mascarenaz AD, Dearth CL, Kaerli M, editors. Diagnostic imaging: brain. Salt Lake City: Amirsys; 2005. p. 32–4.
Shin JL, Asa SL, Woodhouse LJ, et al. Cystic lesions of the pituitary: clinicopathological features distinguishing craniopharyngioma, Rathke’s cleft cyst, and arachnoid cyst. J Clin Endocrinol Metabol. 1999;84:3972–82.
Kornreich L, Blaser S, Schwarz M, et al. Optic pathway glioma: correlation of imaging findings with the presence of neurofibromatosis. AJNR Am J Neuroradiol. 2001;22:1963–9.
Gutenberg A, Larsen J, Lupi I, et al. A radiologic score to distinguish autoimmune hypophysitis from nonsecreting pituitary adenoma preoperatively. AJNR Am J Neuroradiol. 2009;30:1766–72.
Osborne AG. Sella and pituitary. In: Mascarenaz AD, Dearth CL, Kaerli M, editors. Diagnostic imaging: brain. Salt Lake City: Amirsys; 2005. p. 40–1.
Saleem SN, Said A-HM, Lee DH. Lesions of the hypothalamus: MR imaging diagnostic features. Radiographics. 2007;27:1087–108.
Arita K, Ikawa F, Kurisu K, et al. The relationship between magnetic resonance imaging findings and clinical manifestations of hypothalamic hamartoma. J Neurosurg. 1999;91:212–22.
Osborne AG. Sella and pituitary. In: Mascarenaz AD, Dearth CL, Kaerli M, editors. Diagnostic imaging: brain. Salt Lake City: Amirsys; 2005. p. 12–4.
Grois N, Prayer D, Prosch H, et al. Neuropathology of CNS disease in Langerhans cell histiocytosis. Brain. 2005;128:829–38.
Massachusetts General Hospital. Tuberculum sellae meningioma. Accessible at: http://neurosurgery.mgh.harvard.edu/cranialbasecenter/c94.htm. Accessed 1 Dec 2011.
Osborne AG. Skull, scalp, and meninges. In: Mascarenaz AD, Dearth CL, Kaerli M, editors. Diagnostic imaging: brain. Salt Lake City: Amirsys; 2005. p. 56–8.
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Patel, G.V., Karimi, S., Young, R.J. (2013). Sellar and Parasellar Masses. In: Karimi, S. (eds) Atlas of Brain and Spine Oncology Imaging. Atlas of Oncology Imaging. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-5653-7_3
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DOI: https://doi.org/10.1007/978-1-4614-5653-7_3
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