Abstract
With more healthcare providers adopting an electronic medical record, with the ready availability of insurance claims data, and with the availability of government sponsored healthcare databases, it is possible to use data mining and analytic tools to investigate optimal treatment decisions in medical practice. In this chapter, we present several data mining tools that can be used to investigate health outcomes, and we then provide a sample analysis of healthcare data to demonstrate their use. The tools include market basket analysis, text analysis, and predictive modeling. We use these tools to investigate cancer treatments. The need to analyze real data is particularly necessary with the increased prominence of comparative effectiveness analysis.
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References
Cerrito, P.: Text mining techniques for healthcare provider quality determination: methods for rank comparisons. IGI Publishing, Hershey, PA (2009)
Cerrito, P.: Clinical trials versus health outcomes research: SAS/STAT versus SAS enterprise miner. Paper presented at the PharmaSug, Nashville, TN (2011)
Devlin, K.: NHS patients denied drugs due to lack of common sense at NICE, say charities. Telegraph. Retrieved from http://www.telegraph.co.uk/health/healthnews/3531280/NHS-patients-denied-drugs-due-to-lack-of-common-sense-at-Nice-say-charities.html (2008)
Mason, A.R., Drummond, M.F.: Public funding of new cancer drugs: is NICE getting nastier? Eur. J. Canc. 45, 1188–1192 (2009)
Bruno, M.-A., Bernheim, J.L., ledoux, D., Pellas, F., Demertzi, A., Laureys, S.: A survey on self-assessed well-being in a cohort of chronic locked-in syndrome patients: happy majority, miserable minority. BMJ Open. Retrieved from http://bmjopen.bmj.com/content/early/2011/02/16/bmjopen-2010-000039.full (2011)
Anonymous-WSJ. The Avastin Mugging: The FDA rigs the verdict against a good cancer. Wall St. J. Retrieved from http://online.wsj.com/article/SB10001424052748704271804575405203894857436.html (2010)
Perrone, M.: FDA delays decision on breast cancer drug Avastin. AP Associated Press. Retrieved from http://www.msnbc.msn.com/id/39239537/ns/health-cancer/ (2010)
Anonymous-maintenance study. Bevacizumab and combination chemotherapy in treating patients with previously untreated metastatic colorectal cancer that cannot be removed by surgery. (NCt00797485). Retrieved from http://clinicaltrials.gov/ct2/show/NCT00797485 (2009)
Anonymous-bevacizumab. Bevacizumab and cetuximab for the treatment of metastatic colorectal cancer. National Health Service, London (2009)
Giuliani, F., Vita, F.D., Colucci, G., Pisconti, S.: Maintenance therapy in colon cancer. Canc. Treat. Rev. 26(Suppl 3), S42–45 (2010)
Hay, J.W.: Using pharmacoeconomics to value pharmacotherapy. Clin. Pharmacol. Therapeut. 84(2), 197–200 (2008)
Puthillath, A., Patel, A., Fakih, M.G.: Targeted therapies in the management of colorectal carcinoma: role of bevacizumab. Onco. Targets Ther. 2, 1–15 (2009)
Castells, M.C., Tennant, N.M., Sloane, D.E., Hsu, F.I., Barrett, N.A., Hong, D.I., et al.: Hypersensitivity reactions to chemotherapy: outcomes and safety of rapid desensitization in 413 cases. J. Allergy Clin. Immunol. 122, 574–580 (2008)
Togashi, Y., Kim, Y.H., Masago, K., Tamai, K., Sakamori, Y., Mio, T., et al.: Pulmonary embolism due to internal jugular vein thrombosis in a patient with non-small cell lung cancer receiving bevacizumab Retrieved from http://www.springerlink.com/content/0208402248n7mn4k/ (2010)
Acknowledgment
The author wishes to acknowledge the support of Dr. John Cerrito, PharmD, concerning the nature and effects of the drugs discussed in this chapter.
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Cerrito, P. (2013). Clinical Data Mining to Discover Optimal Treatment Patterns. In: Pardalos, P., Georgiev, P., Papajorgji, P., Neugaard, B. (eds) Systems Analysis Tools for Better Health Care Delivery. Springer Optimization and Its Applications, vol 74. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-5094-8_6
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DOI: https://doi.org/10.1007/978-1-4614-5094-8_6
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