Skip to main content

Psychiatric Comorbidity

  • Chapter
  • First Online:
Addressing Unhealthy Alcohol Use in Primary Care
  • 1052 Accesses

Abstract

When a primary care clinician identifies a patient with an alcohol use disorder, there is a high likelihood that this patient has a psychiatric comorbidity. In the National Epidemiologic Survey on Alcoholism and Related Conditions (NESARC), a study representative of the US population, 40.7 % of people who sought treatment for alcohol dependence had at least one mood disorder and 33 % had at least one anxiety disorder [Grant BF, Stinson FS, Dawson DA, et al. Prevalence and Co-occurrence of substance use disorders and independent mood and anxiety disorders. Arch Gen Psychiatry. 2004;61:807–816.]. People who are at-risk drinkers, though they do not meet criteria for dependence or abuse, have higher rates of psychiatric comorbidity than lower risk drinkers or those who abstain from alcohol [Bott K, Meyer C, Rumpf HJ, et al. Psychiatric disorders among at-risk consumers of alcohol in the general population. J Stud Alcgohol. 2005,66: 246–253]. If left untreated, mood, anxiety and other psychiatric disorders can interfere with successful treatment and recovery from alcohol dependence, increase the chance of relapse and lead to overall poorer health outcomes. In the worst-case scenario, these conditions can be fatal, as alcohol use is a significant risk factor for suicide. When treating a patient with an alcohol-related illness, it is important to detect and treat comorbid psychiatric illnesses. It is also important to be able to do an appropriate safety assessment so that a patient can be referred to a higher level of psychiatric care (e.g., psychiatrist, hospital), when necessary.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 64.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 84.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Grant BF, Stinson FS, Dawson DA, et al. Prevalence and Co-occurrence of substance use disorders and independent mood and anxiety disorders. Arch Gen Psychiatry. 2004;61:807–816.

    Article  PubMed  Google Scholar 

  2. Bott K, Meyer C, Rumpf HJ, et al. Psychiatric disorders among at-risk consumers of alcohol in the general population. J Stud Alcgohol. 2005, 66:246–253.

    Google Scholar 

  3. Reiger DA, Farmer ME, Rae DS, et al. Comorbidity of mental disorders with alcohol and other drug abuse:results for the Epidemiologic Catchment Area (ECA) study. JAMA. 1990;264: 2511–2518.

    Article  Google Scholar 

  4. Hasin DS, Goodwin RD, Stinson FS, Grant BF. Epidemiology of major depressive disorder: results from the National Epidemiologic Survey on Alcoholism and Related Conditions. Arch Gen Psychiatry. 2005;62:1097–1106.

    Article  PubMed  Google Scholar 

  5. Tamkin AS, Carson MF, Nixon DH, Hyer LA. A comparison among some measures of depression in male alcoholics. J Stud Alcohol. 1987;48(2):176–178.

    PubMed  CAS  Google Scholar 

  6. Kroenke K, Spitzer RL, Williams JBW. The PHQ-9: validity of a brief depression severity measure. J Gen Intern Med. 2001;16(9):606–613.

    Article  PubMed  CAS  Google Scholar 

  7. Nunes EV, Levin FR. Treatment of depression in patients with alcohol or other drug dependence: A meta-analysis. JAMA. 2004;291(15):1887–1896.

    Article  PubMed  CAS  Google Scholar 

  8. Salloum IM, Cornelius JR, Daley DC, et al. Efficacy of valproate maintenance in patients with bipolar disorder and alcholism: a double-blind, placebo-controlled study. Arch Gen Psychiatry. 2005;62:37–45.

    Article  PubMed  CAS  Google Scholar 

  9. Rubio G, Lopez-Munoz F, Alamo C. Effects of lamotrigine in patients with bipolar disorder and alcohol dependence. Bipolar Disorder. 2006;8:289–293.

    Article  CAS  Google Scholar 

  10. Brown RI, Wolfe J. Substance abuse and post-traumatic stress disorder co-morbidity. Drug Alcohol Depend. 1994;35:51–59

    Article  PubMed  CAS  Google Scholar 

  11. Hien DA, Cohen LR, Miele GM, et al. Promising treatments for women with comorbid PTSD and substance use disorders. Am J Psychiatry. 2004;161:1426–1432.

    Article  PubMed  Google Scholar 

  12. Najavits LM, Weiss RD, Shaw SR, Muenz LR. Seeking Safety: outcome of a new cognitive-behavioral psychotherapy for women with post-traumatic stress disorder and substance dependence. J Traumatic Stress. 1998;11(3):437–456.

    Article  CAS  Google Scholar 

  13. Beck AT, et al. An inventory for measuring clinical anxiety: psychometric properties. J Consulting Clinical Psychology. 1998;56(6):893–897.

    Article  Google Scholar 

  14. Spitzer RL, et al. A brief measure for assessing generalized anxiety disorder: the GAD-7. Arch Int Med. 2006;166(10):1092–1097.

    Article  Google Scholar 

  15. Prins A, Ouimette P, Kimerling R, et al. The primary care PTSD screen (PC-PTSD): development and operating characteristics. Prim Care Psychiatry. 2003;9:9–14.

    Article  Google Scholar 

  16. Barbee JG, Clark, PD, Crapanzano BS, et al. Alcohol and substance abuse among schizophrenic patients presenting to an emergency psychiatric service. Nervous Mental Dis. 1989;177(7):379–441.

    Article  Google Scholar 

  17. Brunette MF, Drake RE, Xie H, et al. Clozapine use and relapses of substance use disorder among patients with co-occurring schizophrenia and substance use disorders. Schizophr Bull. 2006;32:637–643.

    Article  PubMed  Google Scholar 

  18. Beresford TP, Clapp L, Martin B, et al. Aripiprazole in schizophrenia with cocaine dependence: a pilot study. J Clin Psychopharmacol. 2005;25:363–366.

    Article  PubMed  CAS  Google Scholar 

  19. Center for Substance Abuse Treatment. Substance abuse treatment for persons with co-occurring disorders. TIP series 42. HHS Publication No. (SMA) 08-3992. Rockville: SAMHSA; 2005.

    Google Scholar 

  20. Wilens TE, Faraone SV, Biederman J, Gunawardene S. Does stimulant therapy of attention-deficit/hyperactivity disorder beget later substance abuse? A meta-analytic review of the literature. Pediatrics. 2003;111:179–185.

    Article  PubMed  Google Scholar 

  21. Bernal M, Haron JM, Bernet S, et al. Risk factors for suicidality in Europe: results from the ESEMED study. J Affect Disorders. 2007;101:27–34.

    Article  PubMed  CAS  Google Scholar 

  22. Flensbirg-Madsen T, Knop J, Mortensen EL, et al. Alcohol use disorders increase the risk of completed suicide-irrespective of other psychiatric disorders. A longitudinal cohort study. Psych Res. 2009;167:123–130.

    Article  Google Scholar 

  23. Inskip HM, Harris EC, Barraclough B. Lifetime risk of suicide for affective disorder, alcoholism, and schizophrenia. Br J Psychiatry. 1998;172:35–37.

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Amy Harrington .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2013 Springer Science+Business Media New York

About this chapter

Cite this chapter

Harrington, A. (2013). Psychiatric Comorbidity. In: Saitz, R. (eds) Addressing Unhealthy Alcohol Use in Primary Care. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-4779-5_11

Download citation

  • DOI: https://doi.org/10.1007/978-1-4614-4779-5_11

  • Published:

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4614-4778-8

  • Online ISBN: 978-1-4614-4779-5

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics