Abstract
Most farmed animals have anatomical and physiological features that are in many ways similar to humans, but there are also important differences. This chapter assumes a basic understanding of mammalian structure and function and attempts to highlight the differences, particularly as they relate to drug delivery and metabolism. There is a conscious bias towards ruminant livestock, as they represent a major sector of the farmed animal population, and are the group that differ most from the monogastrics. More reading will be required for the reader wishing to develop specific bioactive delivery technologies per se, but this chapter aims to provide a sufficient understanding of the environment into which the drug is being introduced, and an explanation of the relevance of the (sometimes) unusual modes of administration for the reader more interested in the benefits to be gained from the treatment of livestock.
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References
Richardson KC (1984) Forestomach motility in non-ruminant herbivores. In: Baker SK, Gawthorne JM, Mackintosh JB, Purser DB (eds) Ruminant physiology; concepts and consequences. University of Western Australia, Perth, pp 45–55
Reid CSW (1982) Fibre and the digestive physiology of the ruminant stomach. In: Wallace G, Bell I (eds) Fibre in human and animal nutrition. Royal Society of New Zealand, Auckland, NZ, pp 43–49
Hume ID (1984) Evolution of herbivores—the ruminant in perspective. In: Baker SK, Gawthorne JM, Mackintosh JB, Purser DB (eds) Ruminant physiology; concepts and consequences. University of Western Australia, Perth, pp 15–25
Lewis D (1961) In: Lewis (ed) Digestive physiology and nutrition of the ruminant. Proceedings of University of Nottingham 7th Easter School in Agricultural Science, Butterworths, London
Van Soest PJ (1994) In: Van Soest PJ (ed) Nutritional ecology of the ruminant. Cornell University Press, Ithaca, NY
Cronje PJ (2000) In: Cronje PJ (ed) Ruminant physiology, digestion, metabolism, growth and reproduction. University of Pretoria, South Africa
Cardinal JR (2000) Intraruminal controlled release boluses. In: Rathbone MJ, Gurny R (eds) Controlled release veterinary drug delivery: biological and pharmaceutical considerations, Chap. 3. Elsevier, Amsterdam, pp 51–82
Rathbone MJ (1999) Veterinary applications. In: Mathiowitz E (ed) Encyclopedia of controlled drug delivery. Wiley, New York, pp 1006–1037
Vandamme ThF, Ellis KJ (2004) Issues and challenges in developing ruminal drug delivery systems. In: Rathbone M (ed) Advanced drug delivery reviews, vol 56. Elsevier, Amsterdam, pp 1415–1436
Annison EF, Lewis D (1959) In: Annison EF, Lews D (eds) Metabolism in the rumen. Methuen & Co, London, p 15
Costigan P, Ellis KJ (1980) Retention of copper oxide needles in cattle. Proc Aust Soc Anim Prod 13:451
Whitehead L, Fell JT, Collett JH, Sharma HL, Smith AM (1998) Floating dosage forms: an in vivo study demonstrating prolonged gastric retention. J Control Release 55:3–12
Senel S, McClure SJ (2004) Potential applications of chitosan in veterinary medicine. Adv Drug Deliv Rev 56:1467–1480
Baker SK (1984) The rumen as an eco-system. In: Baker SK, Gawthorne JM, Mackintosh JB, Purser DB (eds) Ruminant physiology; concepts and consequences. University of Western Australia, Perth, pp 149–160
Scott TW, Cook LJ, Ferguson KA, McDonald IW, Buchanan RA, Loftus Hills G (1970) Production of polyunsaturated milk fat in domestic ruminants. Aust J Sci 32:291–293
Scott TW, Ashes JR (1993) Dietary lipids for ruminants: protection, utilization and effects on remodelling of skeletal muscle phospholipids. Aust J Agric Res 44:495–508
Desai KGH, Park HJ (2005) Recent developments in microencapsulation of food ingredients. Drying Technol 23:1361–1394
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Ellis, K.J. (2013). Anatomy and Physiology of the Farmed Animal. In: Rathbone, M., McDowell, A. (eds) Long Acting Animal Health Drug Products. Advances in Delivery Science and Technology. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-4439-8_3
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DOI: https://doi.org/10.1007/978-1-4614-4439-8_3
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