Skip to main content
SpringerLink
Log in

Angelica

  • Chapter
  • First Online:
Antioxidant Properties of Spices, Herbs and Other Sources

  • 5346 Accesses

Abstract

Angelica is a hairy plant with fern like leaves and umbels of white flowers and was considered an “Angel’s Herb.” This chapter describes the botany, history, producing regions, flavor and aroma, parts used, and active constituents. The chapter also highlights the uses of angelica in different recipes around the world. Angelica root is the main flavoring ingredient of gin. Angelica has antimutagenic, antiproliferative, cytoprotective, antiseizure, and antioxidant properties. Finally the medicinal uses, functional properties, and antioxidant properties of angelica are discussed in great detail.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 109.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 139.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 199.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  • Chao WW, Kuo YH, Li WC, Lin BF (2009) The production of nitric oxide and prostaglandin E2 in peritoneal macrophages is inhibited by Andrographis paniculata, Angelica sinensis and Morus alba ethyl acetate fractions. J Ethnopharmacol 122(1):68–75

    Article  Google Scholar 

  • Cheng CY, Ho TY, Lee EJ, Su SY, Tang NY, Hsieh CL (2008) Ferulic acid reduces cerebral infarct through its antioxidative and anti-inflammatory effects following transient focal cerebral ischemia in rats. Am J Chin Med 36(6):1105–1119

    Article  CAS  Google Scholar 

  • Chu Q, Hashimoto K, Satoh K, Wang Q, Sakagami H (2009a) Effect of three herbal extracts on NO and PGE2 production by activated mouse macrophage-like cells. In Vivo 23(4):537–544

    CAS  Google Scholar 

  • Chu Q, Satoh K, Kanamoto T, Terakubo S, Nakashima H, Wang Q, Sakagami H (2009b) Antitumor potential of three herbal extracts against human oral squamous cell lines. Anticancer Res 29(8):3211–3219

    Google Scholar 

  • Clevely A, Richmond K (1999) Growing and using herbs. Sebastian Kelly, Oxford

    Google Scholar 

  • Dietz BM, Liu D, Hagos GK, Yao P, Schinkovitz A, Pro SM, Deng S, Farnsworth NR, Pauli GF, van Breemen RB, Bolton JL (2008) Angelica sinensis and its alkylphthalides induce the detoxification enzyme NAD(P)H: quinone oxidoreductase 1 by alkylating Keap1. Chem Res Toxicol 21(10):1939–1948

    Article  CAS  Google Scholar 

  • Hou YZ, Zhao GR, Yang J, Yuan YJ, Zhu GG, Hiltunen R (2004) Protective effect of Ligusticum chuanxiong and Angelica sinensis on endothelial cell damage induced by hydrogen peroxide. Life Sci 75(14):1775–1786

    Article  CAS  Google Scholar 

  • Khayyal MT, el-Ghazaly MA, Kenawy SA, Seif-el-Nasr M, Mahran LG, Kafafi YA, Okpanyi SN (2001) Antiulcerogenic effect of some gastrointestinally acting plant extracts and their combination. Arzneimittelforschung 51(7):545–553

    CAS  Google Scholar 

  • Kim MY, Cheong SH, Kim MH, Son C, Yook HS, Sok DE, Kim JH, Cho Y, Chun H, Kim MR (2009) Leafy vegetable mix supplementation improves lipid profiles and antioxidant status in C57BL/6J mice fed a high fat and high cholesterol diet. J Med Food 12(4):877–884

    Article  CAS  Google Scholar 

  • Kimura T, Hayashida H, Murata M, Takamatsu J (2011) Effect of ferulic acid and Angelica archangelica extract on behavioral and psychological symptoms of dementia in frontotemporal lobar degeneration and dementia with Lewy bodies. Geriatr Gerontol Int 11(3):309–314

    Article  Google Scholar 

  • Li JC, Yang ZR, Zhang K (2002) The intervention effects of Angelica sinensis, Salvia miltiorrhiza and ligustrazine on peritoneal macrophages during peritoneal dialysis. Zhongguo Zhong Xi Yi Jie He Za Zhi 22(3):190–192

    Google Scholar 

  • Li SY, Yu Y, Li SP (2007) Identification of antioxidants in essential oil of radix Angelicae sinensis using HPLC coupled with DAD-MS and ABTS-based assay. J Agric Food Chem 55(9):3358–3362

    Article  CAS  Google Scholar 

  • Liu SP, Dong WG, Wu DF, Luo HS, Yu JP (2003a) Protective effect of angelica sinensis polysaccharide on experimental immunological colon injury in rats. World J Gastroenterol 9(12):2786–2790

    CAS  Google Scholar 

  • Liu JH, Ho SC, Lai TH, Chi PY, Wu RY (2003b) Protective effects of Chinese herbs on D-galactose-induced oxidative damage. Methods Find Exp Clin Pharmacol 25(6):447–452

    Article  Google Scholar 

  • Luo H, Lin S, Ren F, Wu L, Chen L, Sun Y (2007) Antioxidant and antimicrobial capacity of Chinese medicinal herb extracts in raw sheep meat. J Food Prot 70(6):1440–1445

    Google Scholar 

  • Mak DH, Chiu PY, Dong TT, Tsim KW, Ko KM (2006) Dang-Gui Buxue Tang produces a more potent cardioprotective effect than its component herb extracts and enhances glutathione status in rat heart mitochondria and erythrocytes. Phytother Res 20(7):561–567

    Article  Google Scholar 

  • Meng L, Qu L, Tang J, Cai SQ, Wang H, Li X (2007) A combination of Chinese herbs, Astragalus membranaceus var. mongholicus and Angelica sinensis, enhanced nitric oxide production in obstructed rat kidney. Vascul Pharmacol 47(2-3):174–183

    Article  CAS  Google Scholar 

  • Pathak S, Wanjari MM, Jain SK, Tripathi M (2010) Evaluation of antiseizure activity of essential oil from roots of Angelica archangelica Linn. in mice. Indian J Pharm Sci 72(3):371–375

    Article  CAS  Google Scholar 

  • Rhyu MR, Kim JH, Kim EY (2005) Radix angelica elicits both nitric oxide-dependent and calcium influx-mediated relaxation in rat aorta. J Cardiovasc Pharmacol 46(1):99–104

    Article  CAS  Google Scholar 

  • Salikhova RA, Poroshenko GG (1995) Antimutagenic properties of Angelica archangelica L. Vestn Ross Akad Med Nauk 1:58–61

    Google Scholar 

  • Sigurdsson S, Ogmundsdottir HM, Gudbjarnason S (2004) Antiproliferative effect of Angelica archangelica fruits. Z Naturforsch C 59(7–8):523–527

    CAS  Google Scholar 

  • Sigurdsson S, Ogmundsdottir HM, Hallgrimsson J, Gudbjarnason S (2005) Antitumour activity of Angelica archangelica leaf extract. In Vivo 19(1):191–194

    Google Scholar 

  • Thring TS, Hili P, Naughton DP (2009) Anti-collagenase, anti-elastase and anti-oxidant activities of extracts from 21 plants. BMC Complement Altern Med 9:27

    Article  Google Scholar 

  • Wang H, Li W, Li J, Rendon-Mitchell B, Ochani M, Ashok M, Yang L, Yang H, Tracey KJ, Wang P, Sama AE (2006) The aqueous extract of a popular herbal nutrient supplement, Angelica sinensis, protects mice against lethal endotoxemia and sepsis. J Nutr 136(2):360–365

    CAS  Google Scholar 

  • Wedge DE, Klun JA, Tabanca N, Demirci B, Ozek T, Baser KH, Liu Z, Zhang S, Cantrell CL, Zhang J (2009) Bioactivity-guided fractionation and GC/MS fingerprinting of Angelica sinensis and Angelica archangelica root components for antifungal and mosquito deterrent activity. J Agric Food Chem 57:464–470

    Article  CAS  Google Scholar 

  • Wei A, Shibamoto T (2007) Antioxidant activities and volatile constituents of various essential oils. J Agric Food Chem 55(5):1737–1742

    Article  CAS  Google Scholar 

  • Westland P (1987) Angelica. The encyclopedia of herbs and spices. Marshall Cavendish, London

    Google Scholar 

  • Wojcikowski K, Wohlmuth H, Johnson DW, Rolfe M, Gobe G (2009) An in vitro investigation of herbs traditionally used for kidney and urinary system disorders: potential therapeutic and toxic effects. Nephrology (Carlton) 14(1):70–79

    Article  Google Scholar 

  • Wszelaki N, Paradowska K, Jamróz MK, Granica S, Kiss AK (2011) Bioactivity-guided fractionation for the butyrylcholinesterase inhibitory activity of furanocoumarins from Angelica archangelica L. roots and fruits. J Agric Food Chem 59(17):9186–9193

    Article  CAS  Google Scholar 

  • Wu H, Kong L, Wu M, Xi P (1996) Effects of different processed products of radix Angelica sinensis on clearing out oxygen free radicals and anti-lipid peroxidation. Zhongguo Zhong Yao Za Zhi 21(10):599–601

    CAS  Google Scholar 

  • Wu SJ, Ng LT, Lin CC (2004) Antioxidant activities of some common ingredients of traditional Chinese medicine, Angelica sinensis, Lycium barbarum and Poria cocos. Phytother Res 18(12):1008–1012

    Article  Google Scholar 

  • Xin YF, Zhou GL, Shen M, Chen YX, Liu SP, Chen GC, Chen H, You ZQ, Xuan YX (2007) Angelica sinensis: a novel adjunct to prevent doxorubicin-induced chronic cardiotoxicity. Basic Clin Pharmacol Toxicol 101(6):421–426

    Article  CAS  Google Scholar 

  • Yang F, Zhou BR, Zhang P, Zhao YF, Chen J, Liang Y (2007a) Binding of ferulic acid to cytochrome c enhances stability of the protein at physiological pH and inhibits cytochrome c-induced apoptosis. Chem Biol Interact 170(3):231–243

    Article  CAS  Google Scholar 

  • Yang X, Zhao Y, Lv Y, Yang Y, Ruan Y (2007b) Protective effect of polysaccharide fractions from Radix A. sinensis against tert-butylhydroperoxide induced oxidative injury in murine peritoneal macrophages. J Biochem Mol Biol 40(6):928–935

    Article  CAS  Google Scholar 

  • Yang X, Zhao Y, Zhou Y, Lv Y, Mao J, Zhao P (2007c) Component and antioxidant properties of polysaccharide fractions isolated from Angelica sinensis (OLIV.) DIELS. Biol Pharm Bull 30(10):1884–1890

    Article  CAS  Google Scholar 

  • Yang WJ, Li DP, Li JK, Li MH, Chen YL, Zhang PZ (2009) Synergistic antioxidant activities of eight traditional Chinese herb pairs. Biol Pharm Bull 32(6):1021–1026

    Article  CAS  Google Scholar 

  • Yeh ML, Liu CF, Huang CL, Huang TC (2003) Hepatoprotective effect of Angelica archangelica in chronically ethanol-treated mice. Pharmacology 68(2):70–73

    Article  CAS  Google Scholar 

  • Yu Y, Du JR, Wang CY, Qian ZM (2008) Protection against hydrogen peroxide-induced injury by Z-ligustilide in PC12 cells. Exp Brain Res 184(3):307–312

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Frontier Natural Products Co-op, Norway, IA, USA

    Denys J. Charles

Authors
  1. Denys J. Charles
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

Copyright information

© 2012 Springer Science+Business Media New York

About this chapter

Cite this chapter

Charles, D.J. (2012). Angelica. In: Antioxidant Properties of Spices, Herbs and Other Sources. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-4310-0_7

Download citation

Publish with us

Policies and ethics

Search

Navigation