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Implant Infections and Infection-Resistant Materials

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Degradation of Implant Materials

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Abstract

Infection is broadly recognized as one of the most critical and devastating complications associated with the use of biomaterials, particularly in orthopaedic prosthesis surgery.

The idea of combining biomaterials with antimicrobial substances for prophylaxis of infections through local delivery was first developed in dentistry and then the combination of antibiotic cement was proposed also in orthopaedic surgery. Various prophylaxis measures or antimicrobial treatments are analysed and their different efficacies are considered. Different strategies in designing and using infection-resistant and anti-infective biomaterials are presented and discussed.

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Authors and Affiliations

  1. Research Unit on Implant Infections, Rizzoli Orthopaedic Institute, Bologna, Italy

    Davide Campoccia, Lucio Montanaro & Carla Renata Arciola

  2. Experimental Pathology Department, University of Bologna, Via S. Giacomo 14, Bologna, 40126, Italy

    Lucio Montanaro & Carla Renata Arciola

Authors
  1. Davide Campoccia
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  2. Lucio Montanaro
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  3. Carla Renata Arciola
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Corresponding author

Correspondence to Carla Renata Arciola .

Editor information

Editors and Affiliations

  1. Fac. Engineering, School of Mechanical Engineering, Tel Aviv University, Ramat Aviv, Tel-Aviv, 69978, Israel

    Noam Eliaz

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© 2012 Springer Science+Business Media New York

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Campoccia, D., Montanaro, L., Arciola, C.R. (2012). Implant Infections and Infection-Resistant Materials. In: Eliaz, N. (eds) Degradation of Implant Materials. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-3942-4_13

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