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Retinal Detachment and Lens Subluxation in Marfan Syndrome

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Retinal and Choroidal Manifestations of Selected Systemic Diseases

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Abstract

Marfan syndrome is an autosomal dominant inherited disorder of connective tissue. During the last two decades, the major role of mutation of the gene fibrillin 1 was shown. Ocular involvement in Marfan syndrome is very common, and in 41% of Marfan patients, ocular pathology is the presenting symptom. This chapter will detail the two main ocular features: ectopia lentis and retinal detachment-the most common and serious sight-endangering complications of the syndrome. Parallel to improved life expectancy of Marfan patients, the introduction of modern operative instruments changed the surgical approach and significantly improved operative results.

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Author information

Authors and Affiliations

  1. Department of Ophthalmology, Tel Aviv Medical Center, Weizman Street 6, Tel Aviv, 64239, Israel

    Dinah Zur M.D.

  2. Department of Ophthalmology, Tel Aviv Medical Center, Sackler Faculty of Medicine, Tel Aviv University, 6 Weitzman Street, Tel Aviv, 64349, Israel

    Anat Loewenstein M.D., M.H.A.

Authors
  1. Dinah Zur M.D.
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  2. Anat Loewenstein M.D., M.H.A.
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Correspondence to Dinah Zur M.D. .

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Editors and Affiliations

  1. Johns Hopkins University, School of Medicine, The Retina Division,Wilmer Eye Institute, Al-Oruba Street, PO Box 7191, Riyadh, 1010, Saudi Arabia

    J. Fernando Arévalo

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Zur, D., Loewenstein, A. (2013). Retinal Detachment and Lens Subluxation in Marfan Syndrome. In: Arévalo, J. (eds) Retinal and Choroidal Manifestations of Selected Systemic Diseases. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-3646-1_20

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  • DOI: https://doi.org/10.1007/978-1-4614-3646-1_20

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  • Online ISBN: 978-1-4614-3646-1

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