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Tissue Engineering in the Development of Replacement Technologies

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New Technologies for Toxicity Testing

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 745))

Abstract

The field of tissue engineering is generating new scaffolds, bioreactors and methods for stimulating cells within complex cultures, with the aim of recreating the conditions under which cells form functional tissues. Hitherto, the primary focus of this field has been on clinical applications. However, there are many methods of in vitro tissue engineering that represent new opportunities in 3D cell culture and could be the basis for new replacement methods that either replace the use of a tissue isolated from an animal or the use of a living animal. This chapter presents an overview of tissue engineering and provides tissue-specific examples of recent advances.

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Author information

Authors and Affiliations

  1. Wolfson Centre for Stem Cells, Tissue Engineering and Modelling (STEM), Centre Biomolecular for Studies, School of Pharmacy, University of Nottingham, Nottingham, UK

    Kevin M. Shakesheff & Felicity R. A. J. Rose

Authors
  1. Kevin M. Shakesheff
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  2. Felicity R. A. J. Rose
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Corresponding author

Correspondence to Kevin M. Shakesheff .

Editor information

Editors and Affiliations

  1. FRAME, Nottingham, UK

    Michael Balls DPhil

  2. Norwich, UK

    Robert D. Combes PhD (Independent Consultant) (Independent Consultant)

  3. Nottingham, UK

    Nirmala Bhogal PhD (Independent Consultant) (Independent Consultant)

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© 2012 Landes Bioscience and Springer Science+Business Media

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Shakesheff, K.M., Rose, F.R.A.J. (2012). Tissue Engineering in the Development of Replacement Technologies. In: Balls, M., Combes, R.D., Bhogal, N. (eds) New Technologies for Toxicity Testing. Advances in Experimental Medicine and Biology, vol 745. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-3055-1_4

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