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Breastfeeding and Transmission of HIV-1: Epidemiology and Global Magnitude

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Human Immunodeficiency Virus type 1 (HIV-1) and Breastfeeding

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 743))

Abstract

Over the past two decades, major strides have been made in HIV-1 research and prevention. Among these advances, some of the most remarkable and sustained achievements have been in reducing the risk of transmission of HIV-1 from mothers to their infants. In resource-rich settings such as the USA and Europe, mother-to-child transmission (MTCT) of HIV-1 has successfully been reduced to less than 1–2% [1] with the goal of virtual elimination of new cases. This success in prevention of mother-to-child transmission (PMTCT) of HIV-1 has been achieved by widespread implementation of effective PMTCT antiretroviral therapy (ART) regimens, and obstetrical interventions as well as avoidance of breastfeeding through the use of infant formula.

The findings and conclusions in this report are those of the authors and do not necessarily represent the official position of the Centers for Disease Control and Prevention.

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Author information

Authors and Affiliations

  1. Department of Pathology, Johns Hopkins Medical Institutes, Baltimore, MD, USA

    Mary Glenn Fowler M.D., M.P.H.

  2. Onsite Makerere University–Johns Hopkins University Research Collaboration, Kampala, Uganda

    Mary Glenn Fowler M.D., M.P.H.

  3. Division of Reproductive Health, NCCDPHP, Centers for Disease Control and Prevention, 4770 Buford Highway, NE, MSK34, Atlanta, GA, 30341, USA

    Athena P. Kourtis M.D., Ph.D., M.P.H.

  4. Makerere University–Johns Hopkins University Research Collaboration, Upper Mulago Hill Rd, Kampala, Uganda

    Jim Aizire M.B.Ch.B., M.H.S. & Carolyne Onyango-Makumbi M.B.Ch.B., M.S.

  5. Division of Global HIV/AIDS (DGHA), Center for Global Health, Centers for Disease Control and Prevention (CDC), 1600 Clifton Road, NE, Atlanta, GA, 30333, USA

    Marc Bulterys M.D., Ph.D. (Adjunct Professor of Epidemiology)

  6. CDC Global AIDS Program, Beijing, China

    Marc Bulterys M.D., Ph.D. (Adjunct Professor of Epidemiology)

  7. UCLA School of Public Health, Los Angeles, CA, USA

    Marc Bulterys M.D., Ph.D. (Adjunct Professor of Epidemiology)

Authors
  1. Mary Glenn Fowler M.D., M.P.H.
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  2. Athena P. Kourtis M.D., Ph.D., M.P.H.
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  3. Jim Aizire M.B.Ch.B., M.H.S.
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  4. Carolyne Onyango-Makumbi M.B.Ch.B., M.S.
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  5. Marc Bulterys M.D., Ph.D.
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Corresponding author

Correspondence to Mary Glenn Fowler M.D., M.P.H. .

Editor information

Editors and Affiliations

  1. School of Medicine, Emory University, Buford Highway 4770, Atlanta, 30341, Georgia, USA

    Athena P. Kourtis

  2. and Prevention, Global AIDS Program - China, Centers for Disease Control, Emory University School of Medicine, Beijing, 100600, China, People's Republic

    Marc Bulterys

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© 2012 Springer Science+Business Media New York

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Fowler, M.G., Kourtis, A.P., Aizire, J., Onyango-Makumbi, C., Bulterys, M. (2012). Breastfeeding and Transmission of HIV-1: Epidemiology and Global Magnitude. In: Kourtis, A., Bulterys, M. (eds) Human Immunodeficiency Virus type 1 (HIV-1) and Breastfeeding. Advances in Experimental Medicine and Biology, vol 743. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-2251-8_1

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  • DOI: https://doi.org/10.1007/978-1-4614-2251-8_1

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