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Intracellular Dissipative Structures (IDSs)

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Molecular Theory of the Living Cell

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Abstract

According to I. Prigogine (1917–2003) (1977, 1980), there are two fundamental classes of structures in nature – equilibrium structures that can exist without any dissipation of free energy (e.g., crystals, a stick of candle, purified proteins) and dissipative structures whose maintenance requires free energy dissipation (Sect. 3.1) (Kondepudi and Prigogine 1998; Babloyantz 1986; Kondepudi 2008). For convenience, the former has been referred to as equilibrons and the latter as dissipatons (Sect. 3.1.5). The Bhopalator model of the living cell (Ji 1985a, b, 2002b) (to be discussed in Sect. 10.1) postulates that the dissipative structures present inside the living cell (hence called IDSs, or Intracellular Dissipative Structures) play a fundamental role in determining cell functions. The first direct evidence supporting this postulate was provided by the intracellular calcium ion waves observed in chemotaxing human neutrophils using a calcium ion-sensitive fluorescent dye (Sawyer et al. 1985) (see Fig. 3.2 in Sect. 3.1.2).

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  1. Dept. of Pharmacol. & Toxicol. Ernest Mario School of Pharmacy, Rutgers University, Piscataway, NJ, 08854, USA

    Sungchul Ji PhD

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Ji, S. (2012). Intracellular Dissipative Structures (IDSs). In: Molecular Theory of the Living Cell. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-2152-8_9

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  • DOI: https://doi.org/10.1007/978-1-4614-2152-8_9

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