Skip to main content

Bioactive Glasses

  • Chapter
  • First Online:
Glasses and Glass Ceramics for Medical Applications

Abstract

Bioactive glasses were discovered by Hench in 1969 and provided for the first time an alternative interfacial bonding of an implant with host tissues. Bioactive glasses have osteoinductive and osteoconductive properties that can be used for the repair and reconstruction of damaged bone tissues. They are surface-reactive materials designed to induce biological activity and form a strong bond with the living tissues such as bone.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

eBook
USD 16.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Further Reading

  • Cerruti, M., Greenspan, D., Powers, K.: Effect of pH and ionic strength on the reactivity of Bioglass 45 S5. Biomaterials 26, 1665–1674 (2005)

    Article  CAS  Google Scholar 

  • El-Meliegy, E., Hamzawy, E., El-Kady, A., El-Rashedi, A.: Development and bioactivity evaluation of bioglasses with low Na2O content based on the system SiO2-Na2O-CaO- MgO- P2O5. Under Publication

    Google Scholar 

  • El-Meliegy, E.M., El-Bassyouni, G.T.: Study of the bioactivity of fluorophlogopite-whitlockite ceramics. Ceram Int 34(6), 1527–1532 (2008)

    Article  CAS  Google Scholar 

  • EL-Rashedi, A.M.: Preparation and characterization study of bioactive glasses for orthopaedic applications, PhD Thesis, Al-Azhar University, Cairo, Egypt

    Google Scholar 

  • Franks, K., Abrahams, I., Knowles, J.C.: Development of soluble glasses for biomedical use Part I: In vitro solubility measurement. J Mater Sci Mater Med. 11(10), 609–614 (2000)

    Article  CAS  Google Scholar 

  • Gross, U.M., Strunz, V.: J Biomed Mater Res 14, 607 (1980a)

    Article  CAS  Google Scholar 

  • Gross, U.M., Strunz, V.: The anchoring of glass ceramics of different solubility in femur of the rat. J. Biomed. Mater. Res. 14, 607 (1980b)

    Article  CAS  Google Scholar 

  • Hench, L.L.: Bioceramics: from concept to clinic. J Am Ceram Soc 74, 1487 (1991)

    Article  CAS  Google Scholar 

  • Hench, L.L.: The story of Bioglass. J Mater Sci Mater. Med. 17, 967–978 (2006a)

    Article  CAS  Google Scholar 

  • Hench, L.L.: The story of bioglass. J Mater Sci: Mater Med 17, 967–978 (2006b)

    Article  CAS  Google Scholar 

  • Hill, R.G., Stevens, M.M.: Bioactive glass. US patent 0208428, 2009

    Google Scholar 

  • Holand, W.: Biocompatible and bioactive glass-ceramics – state of the art and new directions. J Non Cryst Solids 219, 192–197 (1997)

    Article  Google Scholar 

  • Knowles, J.C., Franks, K., Abrahams, I.: Investigation of the solubility and ion release in the glass system K2O-Na2O-CaO-P2O5. Biomaterials 22, 3091–3096 (2001)

    Article  CAS  Google Scholar 

  • Kokubo, T.: In: Hench, L.L., Wilson, J. (eds.) An Introduction to Bioceramics, p. 75. World Scientific, Singapore (1993)

    Chapter  Google Scholar 

  • Kokubo, T., Takadama, H.: How useful is SBF in predicting in-vivo bone bioactivity. Biomaterials 27, 2907–2915 (2006)

    Article  CAS  Google Scholar 

  • Marikani, A., Maheswaran, A., Premanathan, M., Amalraj, L.: Synthesis and characterization of calcium phosphate based bioactive quaternary P2O5 – CaO – Na2O–K2O glasses. J. Non Cryst. Solids 354, 3929–3934 (2007)

    Article  Google Scholar 

  • Nakamura, T., Yamamuro, T., Higashi, S., Kokubo, T., Itoo, S., Biomed, J.: Mater Res. 19, 685 (1985)

    CAS  Google Scholar 

  • Piotrowski, G., Hench, L.L., Allen, W.C., Miller, G.J.: Mechanical studies of the bone bioglass interfacial bond. J Biomed Mater Res Symp. 9, 47 (1975)

    Article  CAS  Google Scholar 

  • Wilson, J., Yli-Urpo, A., Risto-Pekka, H.: In: Hench, L.L., Wilson, J. (eds.) An Introduction to Bioceramics, p. 63. World Scientific, Singapore (1993)

    Book  Google Scholar 

  • Yamamuro, T.: A/W glass-ceramic: clinical applications. In: Yamamuro, T., Hench, L.L., Wilson, J. (eds.) Handbook of Bioactive Ceramics. Bioactive Glass and Glass Ceramics, vol. 1, p. 89. CRC, Boca Raton, FL (1990)

    Google Scholar 

  • Yamamuro, T.: In: Hench, L.L., Wilson, J. (eds.) An Introduction to Bioceramics, p. 89. World Scientific, Singapore (1993)

    Book  Google Scholar 

  • Yoshii, S., Kakutani, Y., Yamamuro, T., Nakamura, T., Kitsugi, T., Oka, M., Kokubo, T., Takagi, M.: J Biomed Mater Res 22A, 327 (1988)

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Emad El-Meliegy .

Rights and permissions

Reprints and permissions

Copyright information

© 2012 Springer Science+Business Media, LLC

About this chapter

Cite this chapter

El-Meliegy, E., van Noort, R. (2012). Bioactive Glasses. In: Glasses and Glass Ceramics for Medical Applications. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-1228-1_13

Download citation

Publish with us

Policies and ethics