Abstract
Organisms are constantly exposed to foreign compounds, which are either naturally occurring or man-manufactured, and are not normally produced in living cells. Some of these compounds are acutely or potentially toxic, or become toxic and exhibit long-term effects after metabolic conversion. Since their presence in the body could cause a variety of disease conditions, it is essential that the metabolisms catalyzed by phase I enzymes and phase II enzymes maintain these toxic substances at minimum levels. General descriptions of the sources of foreign compounds are presented here, including food, pharmaceuticals, smoking, household and industrial products, and environmental chemicals from the air and water pollution. Potential harmful chemicals that are specifically present in these sources are also discussed below.
An erratum to this chapter can be found at http://dx.doi.org/10.1007/978-1-4614-1049-2_17
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Chen, CH. (2012). Sources of Foreign Compounds. In: Activation and Detoxification Enzymes. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-1049-2_13
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DOI: https://doi.org/10.1007/978-1-4614-1049-2_13
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