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Bioactive Metals Prepared by Surface Modification: Preparation and Properties

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Applications of Electrochemistry and Nanotechnology in Biology and Medicine I

Part of the book series: Modern Aspects of Electrochemistry ((MAOE,volume 52))

Abstract

In general, synthetic materials implanted into bone defects are en-capsulated by a fibrous tissue that isolates them from the sur-rounding bone, and hence do not fix to the surrounding bone well. Several types of ceramics based on calcium phosphate, such as Bioglass in the Na2O-CaO-SiO2-P2O5 system, glass-ceramic A-W in the MgO-CaO-SiO2-P2O5 system, sintered hydroxyapatite, sintered β-tricalcium phosphate, and a combination of these two phases, have been found to bond to bone directly without forming any fibrous tissue around them.1 They are called bioactive ceramics, and are already used clinically as important bone substitutes. However, they are brittle and have poor fracture toughness, and hence cannot be used under load-bearing conditions.

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  1. Department of Biomedical Sciences, College of Life and Health Sciences, Chubu University, 1200 Matsumoto-cho, Kasugai, 487-8501, Japan

    Professor Tadashi Kokubo & Dr. Seiji Yamaguchi

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Correspondence to Tadashi Kokubo .

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  1. Fac. Engineering, School of Mechanical Engineering, Tel Aviv University, Ramat Aviv, Tel-Aviv, 69978, Israel

    Noam Eliaz

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Kokubo, T., Yamaguchi, S. (2011). Bioactive Metals Prepared by Surface Modification: Preparation and Properties. In: Eliaz, N. (eds) Applications of Electrochemistry and Nanotechnology in Biology and Medicine I. Modern Aspects of Electrochemistry, vol 52. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-0347-0_6

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