Abstract
Mesenchymal tumors of the liver are rare and account for lesser than 5% of all primary hepatic neoplasms. They are usually large, radiographically apparent tumors that are evaluated in the preoperative setting, although the diagnosis may be first suggested during surgical exploration in some cases. Most pediatric liver tumors contain mesenchymal elements with, or without, an epithelial component. These lesions are also uncommon and may not be detected before they achieve a large size. Surgical resection is the treatment of choice for mesenchymal tumors of adults and children. Intraoperative consultation is generally obtained for two purposes: (1) assessing the adequacy of resection and (2) providing information regarding tumor classification.
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References
Flemming P, Lang H, Georgii A. Mesenchymal tumors of the liver: their frequency and histopathologic diagnostic problems in surgical investigations. Verh Dtsch Ges Pathol. 1995;79:116–9.
Hornick JL, Fletcher CD. PEComa: what do we know so far? Histopathology. 2006;48(1):75–82.
Rouquie D, Eggenspieler P, Algayres JP, Bechade D, Camparo P, Baranger B. Malignant-like angiomyolipoma of the liver: report of one case and review of the literature. Ann Chir. 2006;131(5):338–41.
Bioulac-Sage P, Laumonier H, Laurent C, Blanc JF, Balabaud C. Benign and malignant vascular tumors of the liver in adults. Semin Liver Dis. 2008;28(3):302–14.
Kim T, Hori M, Onishi H. Liver masses with a central or eccentric scar. Semin Ultrasound CT MR. 2009;30(5):418–25.
Mosoia L, Mabrut J-Y, Adham M, et al. Hepatic epithelioid hemangioendothelioma: long-term results of surgical management. J Surg Oncol. 2008;98:432–7.
Ercolani G, Grazi GL, Pinna AD. Liver transplantation for benign hepatic tumors: a systematic review. Dig Surg. 2010;27(1):68–75.
Mehrabi A, Kashfi A, Fonouni H, et al. Primary malignant hepatic epithelioid hemangioendothelioma: a comprehensive review of the literature with emphasis on the surgical therapy. Cancer. 2006;107(9):2108–21.
Bonaccorsi-Riani E, Lerut JP. Liver transplantation and vascular tumors. Transpl Int. 2010;23(7):686–91.
Weiss SW, Enzinger FM. Epithelioid hemangioendothelioma: a vascular tumor often mistaken for a carcinoma. Cancer. 1982;50(5):970–81.
Bolt HM. Vinyl chloride-a classical industrial toxicant of new interest. Crit Rev Toxicol. 2005;35(4):307–23.
Husted TL, Neff G, Thomas MJ, Gross TG, Woodle ES, Buell JF. Liver transplantation for primary or metastatic sarcoma to the liver. Am J Transplant. 2006;6:392–7.
Weitz J, Klimstra DS, Cymes K, et al. Management of primary liver sarcomas. Cancer. 2007;109(7):1391–6.
Deyrup AT. Epstein-Barr virus-associated epithelial and mesenchymal neoplasms. Hum Pathol. 2008;39(4):473–83.
Cheuk W, Li PC, Chan JK. Epstein-Barr virus-associated smooth Âmuscle tumour: a distinctive mesenchymal tumour of immunocompromised individuals. Pathology. 2002;34(3):245–9.
Kovach SJ, Fischer AC, Katzman PJ, et al. Inflammatory myofibroblastic tumors. J Surg Oncol. 2006;94(5):385–91.
Ozkan EE, Gulder ME, Uzunkoy A. A case report of benign schwannoma of the liver. Intern Med. 2010;49(15):1533–6.
Lee WH, Kim TH, You SS, et al. Benign schwannoma of the liver: a case report. J Korean Med Sci. 2008;23(4):727–30.
Mushtaq S, Mamoon N, Hassan U, Iqbal M, Khadim MT, Sarfraz T. Gastrointestinal stromal tumors-a morphologic and immunohistochemical study. J Gastrointest Cancer. 2009;40:109–14.
Garber JE, Li FP, Kingston JE, et al. Hepatoblastoma and familial adenomatous polyposis. J Natl Cancer Inst. 1988;80(20):1626–8.
Hughes LJ, Michels VV. Risk of hepatoblastoma in familial adenomatous polyposis. Am J Med Genet. 1992;43(6):1023–5.
Fuchs J, Rydzynski J, von Schweinitz D, et al. Pretreatment prognostic factors and treatment results in childhood hepatoblastoma: a report from the German Cooperative Pediatric Liver Tumor Study HB 94. Cancer. 2002;95(1):172–82.
Pritchard J, Stringer M. Outcome and complications after resection of hepatoblastoma. J Pediatr Surg. 2004;39(11):1743–4.
Czauderna P, Otto JB, Roebuck DJ, von Schweinitz D, Plaschkes J. Surgical treatment of hepatoblastoma in children. Pediatr Radiol. 2006;36(3):187–91.
Kelly M, Martin L, Alonso M, Altura R. Liver transplant for relapsed undifferentiated embryonal sarcoma in a young child. J Pediatr Surg. 2009;44(12):e1–3.
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Yantiss, R.K. (2011). Mesenchymal and Pediatric Tumors of the Liver. In: Yantiss, R. (eds) Frozen Section Library: Liver, Extrahepatic Biliary Tree and Gallbladder. Frozen Section Library. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-0043-1_4
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DOI: https://doi.org/10.1007/978-1-4614-0043-1_4
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