Abstract
In 1966, Laron et al., in Israel, described a genetic form of dwarfism in three siblings with physical features similar to growth hormone (GH) deficiency, but with abnormally high serum levels of immunoreactive GH (1). In subsequent reports, they described 29 patients in Israel, primarily of Oriental Jewish ancestry from North Africa and the Persian Gulf (2, 3). An additional 70 subjects have been reported (4), many of Mediterranean ancestry, including individuals from Iran, Iraq, Yemen, Tunisia, Lebanon, Saudi Arabia, Algeria, France, Italy, Sardinia, Spain, Brazil, Argentina, Mexico, Pakistan, Bangladesh, northern Europe, Japan, South Africa, Canada, and the United States.
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References
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© 1994 Springer-Verlag New York, Inc.
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Cohen, P. et al. (1994). Medical and Scientific Aspects of Growth Hormone Receptor Deficiency (Laron Syndrome) in Ecuador. In: Bercu, B.B., Walker, R.F. (eds) Growth Hormone II. Serono Symposia USA Norwell, Massachusetts. Springer, New York, NY. https://doi.org/10.1007/978-1-4613-8372-7_21
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DOI: https://doi.org/10.1007/978-1-4613-8372-7_21
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