Abstract
The anatomical pathology, i.e., the gross and microscopic study of the effects of Trichinella infection on the organs and tissues of the host, is the subject of this chapter. The material presented is limited primarily to those studies that used small laboratory animals and conventional histological techniques. Ultrastructural changes, as detected by various electron-microscopic techniques, are described elsewhere.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Al Karmi, T.O., and Faubert, G.M., 1981, Comparative analysis of mobility and ultra-structure of intramuscular larvae of Trichinella spiralis and Trichinella pseudospiralis, J. Parasitol. 67: 685–691.
Beresantev, Y.-A., 1962, On the relationship of trichinellae to the wall of the intestine, Wiad. Parazytol. 8: 57–61.
Bernard, G.R., and Sudak, F.N., 1960, Experimental trichinosis in the golden hamster. II. Electrocardiographic changes, Am. Heart J. 60: 88–93.
Boyd, E.M., and Huston, E.J., 1954, The distribution, longevity, and sex ratio of Trichinella spiralis in hamsters following an initial infection, J. Parasitol. 40: 686–690.
Bruce, R.G., 1970, The structure and development of the capsule of Trichinella spiralis, J. Parasitol. 56: 38–39.
Bullock, W.L., 1953, Phosphatases in experimental Trichinella spiralis infections in the rat, Exp. Parasitol. 2: 150–162.
Campbell, W.C., and Cuckler, A.C., 1966, Further studies on the effect of thiabendazole on trichinosis in swine, with notes on the biology of the infection, J. Parasitol. 52: 260–279.
Castro, G.A., Olson, L.J., and Baker, R.D., 1967, Glucose malabsorption and intestinal histopathology in Trichinella spiralis-infected guinea pigs, J. Parasitol. 53: 595–612.
Castro, G.A., Johnson, L.R., Copeland, E.M., and Dudrick, S.J., 1974, Development of enteric parasites in parenterally fed rats, Proc. Soc. Exp. Biol. Med. 146: 703–706.
Catty, D., 1969, The immunology of nematode infections: Trichinosis in guinea pigs as a model, in: Monographs in Allergy, Vol. 5 (P. Kallos, M. Hasek, T.M. Inderbitzin, P.A. Miescher, and B.K. Waksman, eds.), S. Karger, Basel, pp. 1–134.
Despommier, D., 1976, Musculature, in: Ecological Aspects of Parasitology (C.R. Kennedy, ed.), North-Holland, Amsterdam, pp. 269–285.
Drachman, D.A., and Tunchay, T.O., 1965, The remote pathology of trichinosis, Neurology 15: 1127–1135.
Dunlap, G.L., and Weiler, C.V., 1933, Pathogenesis of trichinous myocarditis, Proc. Soc. Exp. Biol. Med. 30: 1261–1262.
Edwards, J.L., and Hood, C.I., 1962, Studies on the pathogenesis of cardiac and cerebral lesions of experimental trichinosis in rabbits, Am. J. Pathol. 40: 711–717.
Foldes, J., 1953, Acute trichinosis with finding of larva in bone marrow, Am. J. Clin. Pathol. 23: 918–920.
Gabryel, P., Gustowski, L., Blotna-Filipiak, M., and Rauhut, W., 1978, Pathomorphology of mouse muscle tissue during Trichinella pseudospiralis (light-and electronmicroscopic observations), in: Trichinellosis, Proceedings of the Fourth International Conference on Trichinellosis (C.W. Kim and Z.S. Pawłowski, eds.), University Press of New England, Hanover, New Hampshire, pp. 281–294.
Gardiner, C.H., 1976, Habitat and reproductive behavior of Trichinella spiralis, J. Parasitol. 62: 865–870.
Gould, S.E., 1954, The eye and orbit in trichinosis, Bull. N. Y. Acad. Med. 30: 726–729.
Gould, S.E., (ed.), 1970, Trichinosis in Man and Animals, Charles C. Thomas, Springfield, Illinois.
Grove, D.I., Hamburger, J., and Warren, K.S., 1977, Kinetics of immunological responses, resistance to reinfection, and pathological reactions to infection with Trichinella spiralis, J. Infect. Dis. 136: 562–570.
Gursch, O.F., 1949, Intestinal phase of Trichinella spiralis (Owen, 1835) Railliet, 1895, J. Parasitol. 35: 19–26.
Gustowski, L., Ruitenberg, E.J., and Elgersma, A., 1980, Cellular reactions in tongue and gut in murine trichinellosis and their thymus-dependence, Parasite Immunol. 2: 133–154.
Harley, J.P., 1972, Size of Trichinella spiralis (Nematoda) muscle cysts in the rat, mouse, and guinea-pig, Experientia 28: 486–487.
Hill, C.H., 1957, Distribution of larvae of Trichinella spiralis in the organs of experimentally infected swine, J. Parasitol. 43: 574–577.
Humes, A.G., and Akers, R.P., 1952, Vascular changes in the cheek pouch of the golden hamster during infection with Trichinella spiralis larvae, Anat. Rec. 114: 103–111.
Ismail, M.M., and Tanner, C.E., 1972, Trichinella spiralis: Peripheral blood, intestinal, and bone-marrow eosinophilia in rats and its relationship to the inoculating dose of larvae, antibody response and parasitism, Exp. Parasitol. 31: 262–272.
Kean, H., 1966, Cancer and trichinosis of the larynx, Laryngoscope 76: 1766–1768.
Kennedy, M.W., 1978, Kinetics of establishment, distribution, and expulsion of the enterai phase of Trichinella spiralis in the NIH strain of mouse, in: Trichinellosis, Proceedings of the Fourth International Conference on Trichinellosis (C.W. Kim and Z.S. Pawłowski, eds.), University Press of New England, Hanover, New Hampshire, pp. 193–205.
Larsh, J.E., 1963, Experimental trichiniasis, in: Advances in Parasitology, Vol. 1 (B. Dawes, ed.), Academic Press, New York, pp. 213–286.
Larsh, J.E., and Race, G.J., 1954, A histopathologic study of the anterior small intestine of immunized and nonimmunized mice infected with Trichinella spiralis, J. Infect. Dis. 94: 262–272.
Larsh, J.E., and Race, G.J., 1975, Allergic inflammation as a hypothesis for the expulsion of worms from tissues: A review, Exp. Parasitol. 37: 251–266.
Larsh, J.E., Race, G.J., and Jeffries, W.B., 1954, The association in young mice of intestinal inflammation and the loss of adult worms following an initial infection with Trichinella spiralis, J. Infect. Dis. 99: 63–71.
Larsh, J.E., Race G.J., and Yarinsky, A., 1962, A histopathologic study in mice immunized against Trichinella spiralis and exposed to total-body X-irradiation, Am. J. Trop. Med. Hyg. 11: 633–640.
Larsh, J.E., Race, G.J., Martin, J.H., and Weatherly, N.F., 1974, Studies on delayed (cellular) hypersensitivity in mice infected with Trichinella spiralis. VIII. Serologic and histopathologic responses of recipients injected with spleen cells from donors suppressed with ATS, J. Parasitol. 60: 99–109.
Leonard, A.B., and Beahm, E.H., 1941, Studies on the distribution of Trichinella larvae in the albino rat, Trans. Kansas Acad. Sci 44: 429–433.
Lin, T.-M., and Olson, L.J., 1970, Pathophysiology of reinfection with Trichinella spiralis in guinea pigs during the intestinal phase, J. Parasitol. 56: 529–539.
Marty, W.G., 1966, The intestinal phase of experimental infection of chicks with Trichinella spiralis, J. Parasitol. 52: 903–907.
Matoff, K., and Komandarev, S., 1964, Further investigations into the problem of muscle trichinae occurrence in organs devoid of striated muscles, Wiad. Parazytol. 10: 639–650.
Mauss, E.A., and Otto, G.F., 1942, The occurrence of Trichinella spiralis larvae in tissues other than skeletal muscles, J. Lab. Clin. Med. 27: 1384–1387.
Mikhail, E.G., Milad, M., Sabet, S., and Abdallah, A., 1978, Experimental trichinosis. I. A pathological study of hepatic, renal, and gonadal involvement, J. Egypt. Public Health Assoc. 53: 327–340.
Most, H., and Abeles, M.M., 1937, Trichiniasis involving the nervous system: A clinical and neuropathologic review, with report of two cases, Arch. Neurol. Psychiatry 37: 589–616.
Murray, M., Miller, H.R.P., and Jarrett, W.F.H., 1968, The globule leucocyte and its derivation from the subepithelial mast cell, Lab. Invest. 19: 222–234.
Nelson, G.S., and Mukundi, J., 1962, The distribution of Trichinella spiralis larvae in the muscles of primates, Wiad. Parazytol. 8: 629–632.
Offutt, E.P., and McCoy, O.R., 1941, The “gopher,” Citellus richardsonii (Sabine) as an experimental host for Trichinella spiralis, J. Parasitol. 27: 535–538.
Ogielski, L., 1949, Reaction of the vascular vessels against an invasion of the larvae of Trichinella spiralis, Zool. Pol. 5: 34–42.
Olsen, B.S., Villella, J.B., and Gould, S.E., 1964, Distribution of Trichinella spiralis in muscles of experimentally infected swine, J. Parasitol. 50: 489–495.
Opie, E.L., 1904, An experimental study of the relation of cells with eosinophil granulation to infection with an animal parasite (Trichinella spiralis), Am.J. Med. Sci. 127: 477–493.
Pambuccian, G., and Cironeanu, I., 1961, Observations on experimental trichinellosis in white rats: A pathological and clinical study, Rum. Med. Rev. 6: 8–13.
Race, G.J., Larsh, J.E., Martin, J.H., and Weatherly, N.F., 1974, Light and electron microscopy of the intestinal tissue of mice parasitized by Trichinella spiralis, in: Trichinellosis, Proceedings of the Third International Conference on Trichinellosis (C.W. Kim, ed.), Intext, New York, pp. 75–100.
Race, G.J., Larsh, J.E., Martin, J.H., Weatherly, N.F., and Goulson, H.T., 1978, Histo-pathologic observations of mice after expulsion of Trichinella spiralis, in: Trichinellosis, Proceedings of the Fourth International Conference on Trichinellosis (C.W. Kim and Z.S. Pawłowski, eds.), University Press of New England, Hanover, New Hampshire, pp. 239–261.
Ritterson, A.L., 1957, The Chinese hamster (Cricetulus griseus) as an experimental host for Trichinella spiralis, J. Parasitol. 43: 542–547.
Roth, H., 1938, On the localization of adult trichinae in the intestine, J. Parasitol. 24: 225–331.
Roth, H., 1939, Experimental studies on the course of trichina infection in guinea pigs. II. Natural susceptibility of the guinea pig to experimental trichina infection, Am. J. Hyg. 29: 89–104.
Ruitenberg, E.J., and Elgersma, A., 1976, Absence of intestinal mast cell response in congenitally athymic mice during Trichinella spiralis infection, Nature (London) 264: 258–260.
Ruitenberg, E.J., and Elgersma, A., 1980, Study of the kinetics of globule leucocytes in the intestinal epithelium of rats after single or double infection with Trichinella spiralis, Br. J. Exp. Pathol. 61: 285–290.
Ruitenberg, E.J., Leenstra, F., and Elgersma, A., 1977, Thymus dependence and independence of intestinal pathology in a Trichinella spiralis infection: A study in congenitally athymic (nude) mice, Br. J. Exp. Pathol. 58: 311–314.
Shanta, C.S., and Meerovitch, E., 1967, The life cycle of Trichinella spiralis. II. The muscle phase of development and its possible evolution, Can. J. Zool. 45: 1261–1267.
Stewart, G.L., and Charniga, L.M., 1980, Distribution of Trichinella spiralis in muscles of the mouse, J. Parasitol. 66: 688–689.
Tanner, C.E., 1968, Relationship between infecting dose, muscle parasitism, and antibody response in experimental trichinosis in rabbits, J. Parasitol. 54: 98–107.
Teppema, J.S., Robinson, J.E., and Ruitenberg, E.J., 1973, Ultrastructural aspects of capsule formation in Trichinella spiralis infection in the rat, Parasitology 66: 291–296.
Teppema, J.S., Blomjous, F.J.E.M., Elgersma, A., and Ruitenberg, E.J., 1981, Trichinella pseudospiralis and T. spiralis infections in monkeys. III. Pathological aspects, in: Trichinellosis, Proceedings of the Fifth International Conference on Trichinellosis (C.W. Kim, E.J. Ruitenberg, and J.S. Teppema, eds.), Reedbooks, Chertsey, Surrey, England, pp. 209–214.
Walls, R.S., Carter, R.L., Leuchars, E., and Davies, A.J.S., 1973, The immunopathology of trichiniasis in T-cell deficient mice, Clin. Exp. Immunol. 13: 231–242.
Wright, K.A., 1979, Trichinella spiralis: An intracellular parasite in the intestinal phase, J. Parasitol. 65: 441–445.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1983 Plenum Press, New York
About this chapter
Cite this chapter
Weatherly, N.F. (1983). Anatomical Pathology. In: Campbell, W.C. (eds) Trichinella and Trichinosis. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-3578-8_5
Download citation
DOI: https://doi.org/10.1007/978-1-4613-3578-8_5
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4613-3580-1
Online ISBN: 978-1-4613-3578-8
eBook Packages: Springer Book Archive