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Allogeneic Marrow Transplantation for Acute Nonlymphoblastic Leukemia in Adults

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Biology and Therapy of Acute Leukemia

Part of the book series: Developments in Oncology ((DION,volume 33))

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Abstract

Over the past decade, marrow transplantation has progressed from a very experimental approach applied only to a handful of endstage leukemic patients to an important therapeutic option appropriate for many patients. In this paper we will describe the role marrow transplantation plays in the treatment of acute nonlymphoblastic leukemia (ANL) in adults. In order to define this role, the outcome of marrow transplantation obviously must be compared to that of more conventional chemotherapy for specific patient groups at given stages of their disease. Such comparisons are best made in prospective studies but only a few such studies have been performed and completed. For many patient groups only retrospective comparisons are possible. Retrospective analyses are inherently flawed and serve only as estimates. For some patient groups not even retrospective comparisons are possible because adequate data are not available.

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© 1985 Martinus Nijhoff Publishing, Boston

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Appelbaum, F.R., Thomas, E.D. (1985). Allogeneic Marrow Transplantation for Acute Nonlymphoblastic Leukemia in Adults. In: Baker, L., Valeriote, F., Ratanatharathorn, V. (eds) Biology and Therapy of Acute Leukemia. Developments in Oncology, vol 33. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2609-0_12

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  • DOI: https://doi.org/10.1007/978-1-4613-2609-0_12

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-9633-1

  • Online ISBN: 978-1-4613-2609-0

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