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In Vivo Neutron Activation Analysis

  • Conference paper
Quality of the Body Cell Mass

Part of the book series: Serono Symposia USA ((SERONOSYMP))

Abstract

It is more than 30 years since the first measurements of the elemental composition of the human body were undertaken (Anderson 1964) using the technique of in vivo neutron activation analysis (IVNAA). The work followed a report of two nuclear reactor accidents during which 10 persons were exposed to bursts of fast neutrons and gamma rays (Hoffman 1957). Following the accident a measure of the serum 24Na activity induced in the body was used to estimate the neutron intensity to which the subjects had been exposed. It was subsequently realized that a controlled irradiation with neutrons of known intensity could be used as an investigative tool. To date measurement of both bulk (e.g., Ca, C, Cl, H, N, Na, O, and P) and trace (e.g., Al, Cd, Cu, Fe, and Si) elements has been utilized. Of these, measurements of Ca, Cd, and N, and, more recently C, have enjoyed the greatest clinical application. Review papers on the techniques and clinical applications of IVNAA (Cohn 1981, Chettle 1984, Beddoe 1985, Cohn 1985, Hill 1992, Ryde 1995) provide excellent sources of information. Proceedings from the “In vivo Body Composition Studies” series of Symposia (Ellis 1987, Yasumura 1990, Ellis 1993, Mattsson, 1997) provide valuable sources of developments in IVNAA.

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Authors
  1. Simon J. S. Ryde
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Editors and Affiliations

  1. Nutrition Research Center, St. Luke’-Roosevelt Hospital Center, New York, NY, 10025, USA

    Richard N. Pierson Jr. M.D.

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© 2000 Springer-Verlag New York, Inc.

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Ryde, S.J.S. (2000). In Vivo Neutron Activation Analysis. In: Pierson, R.N. (eds) Quality of the Body Cell Mass. Serono Symposia USA. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-2090-9_10

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  • DOI: https://doi.org/10.1007/978-1-4612-2090-9_10

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4612-7410-0

  • Online ISBN: 978-1-4612-2090-9

  • eBook Packages: Springer Book Archive

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