Abstract
Turner syndrome (TS) affects approximately 1:2000 live-born females (1). Thus, it has a prevalence only one fourth that of Klinefelter syndrome, although it is a far more frequent cause of referral to pediatric endocrinologists. This can be attributed to the fact that the Turner phenotype is much more evident during childhood than is the case for Klinefelter syndrome. Congenital heart abnormalities or lymphedema may be evident prenatally (as ascertained by ultrasonography) or at birth; growth abnormalities may be apparent during childhood, and pubertal delay is observed in approximately 80% of TS girls. Any of these abnormalities should alert the physician to the possible diagnosis of TS.
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Rosenfeld, R.G. (2000). The Impact of Growth Hormone Therapy on Turner Syndrome. In: Stabler, B., Bercu, B.B. (eds) Therapeutic Outcome of Endocrine Disorders. Serono Symposia USA. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-1230-0_7
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DOI: https://doi.org/10.1007/978-1-4612-1230-0_7
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