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Diabetes and Metabolic Syndrome

  • Chapter
Air Pollution and Health Effects

Part of the book series: Molecular and Integrative Toxicology ((MOLECUL))

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Abstract

Diabetes is one of the major health challenges in the United States and worldwide. There are ~8.3 % of Americans have diabetes, with type 2 diabetes accounts for 95 % of the cases. Both human and animal studies have suggested that air pollution is an important environmental risk factor for diabetes and metabolic syndrome. However, the underlying mechanism are largely unknown. Recent studies indicate multiple system and mechanisms involved in this process. In this chapter, we will summarize both epidemiological and experimental evidence showing the promotive effect of air pollution on diabetes.

*Author contributed equally with all other contributors.

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Acknowledgement

This work was supported by a grant from US EPA (R834797) and grants from NIH (RO1 ES015146, R01ES017290 and R21 DK088522).

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    Authors and Affiliations

    1. Division of Cardiovascular Medicine, Department of Medicine, University of Maryland School of Medicine, 110 S. Paca St., 7th floor, Room 7-N-100, Baltimore, 21201, MD, USA

      Xiaoquan Rao M.D., Ph.D. & Sanjay Rajagopalan M.D.

    2. Davis Heart and Lung Research Institute, The Ohio State University, Columbus, OH, USA

      Cuiqing Liu Ph.D.

    3. Department of Physiology, Medical College, Hangzhou Normal University, Hangzhou, Zhejiang, China

      Cuiqing Liu Ph.D.

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    1. Xiaoquan Rao M.D., Ph.D.
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    2. Cuiqing Liu Ph.D.
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    3. Sanjay Rajagopalan M.D.
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    Correspondence to Sanjay Rajagopalan M.D. .

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    Editors and Affiliations

    1. Division of Extramural Research and Training, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina, USA

      Srikanth S. Nadadur

    2. Department of Internal Medicine, Division of Pulmonary, Allergy, Critical Care, and Sleep Medicine, Ohio State University, Columbus, Ohio, USA

      John W. Hollingsworth

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    Rao, X., Liu, C., Rajagopalan, S. (2015). Diabetes and Metabolic Syndrome. In: Nadadur, S., Hollingsworth, J. (eds) Air Pollution and Health Effects. Molecular and Integrative Toxicology. Springer, London. https://doi.org/10.1007/978-1-4471-6669-6_8

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