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Oxidative Stress and Hypertension

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Blood Pressure and Arterial Wall Mechanics in Cardiovascular Diseases

Abstract

In the past 20 years, it has become clear that reactive oxygen species (ROS) contribute to the development of hypertension via myriad effects. While ROS are essential for normal cell function, they mediate pathological changes in the brain, the kidney and blood vessels associated with the genesis of chronic hypertension.

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Authors and Affiliations

  1. Division of Clinical Pharmacology, Departments of Medicine and Pharmacology, Vanderbilt University School of Medicine, Nashville, TN, 37232-6602, USA

    Jing Wu & David G. Harrison MD

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  1. Jing Wu
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Editors and Affiliations

  1. Hôtel-Dieu Hospital Diagnosis and Therapeutics Center, Paris Descartes University, Paris, Paris, France

    Michel E. Safar

  2. St Vincent Clinic and Hospital, University of New South Wales, Victor Chang Cardiac Research Institute, Darlinghurst, Sydney, New South Wales, Australia

    Michael F. O'Rourke

  3. Department of Cardiology, Ochsner Clinic Foundation, New Orleans, Louisiana, USA

    Edward D. Frohlich

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Wu, J., Harrison, D.G. (2014). Oxidative Stress and Hypertension. In: Safar, M., O'Rourke, M., Frohlich, E. (eds) Blood Pressure and Arterial Wall Mechanics in Cardiovascular Diseases. Springer, London. https://doi.org/10.1007/978-1-4471-5198-2_15

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