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Directions in Clinical Research on ATOS

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Thoracic Outlet Syndrome

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Abstract

Arterial thoracic outlet syndrome (TOS) is the least frequent but likely most complex form of TOS. It most frequently occurs in relatively young, active, and otherwise healthy individuals. It is primarily caused by bony abnormalities, such as cervical ribs and anomalous first ribs. In this condition, longstanding subclavian artery compression leads to poststenotic dilatation and ulceration or aneurysmal degeneration, followed by occlusive thrombosis or mural thrombus formation with distal embolization to the arm and/or hand. Many clinical questions regarding diagnosis and optimal management of arterial TOS remain unanswered. The development of an international registry for patients with arterial TOS, along with standards for characterizing patients and reporting clinical outcomes, would provide useful data to help guide the optimal management of this rare and challenging clinical condition.

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Author information

Authors and Affiliations

  1. Department of Cardiothoracic and Vascular Surgery, University of Texas Medical School, Memorial Hermann Heart and Vascular Institute, 6400 Fannin St., Suite 2850, Houston, TX, 77030, USA

    Ali Azizzadeh MD, FACS

  2. Department of Vascular and Endovascular Surgery, Brigham and Women’s Hospital, 75 Francis Street, Boston, MA, 02115, USA

    Louis L. Nguyen MD, MBA, MPH

  3. Department of Surgery, Section of Vascular Surgery, Center for Thoracic Outlet Syndrome, Washington University, Barnes-Jewish Hospital, Campus Box 8109/Suite 5101 Queeny Tower,660 S Euclid Avenue, St. Louis, MO, 63110, USA

    Robert W. Thompson MD

Authors
  1. Ali Azizzadeh MD, FACS
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  2. Louis L. Nguyen MD, MBA, MPH
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  3. Robert W. Thompson MD
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Corresponding author

Correspondence to Ali Azizzadeh MD, FACS .

Editor information

Editors and Affiliations

  1. , Division of Vascular Surgery, University of South Florida, Tampa General Circle, STC 7016 2, Tampa, 33606, Florida, USA

    Karl A. Illig

  2. Barnes-Jewish Hospital, Department of Surgery, Washington University, Queeny Tower Campus Box, St. Louis, 63110, Missouri, USA

    Robert W. Thompson

  3. , Department of Surgery, John Hopkins Medical Institutions, Rutland Avenue - Ross 759 729, Baltimore, 21205, Maryland, USA

    Julie Ann Freischlag

  4. , Department of Thoracic Surgery, Blake 15, Massachusetts General Hospital, Fruit Street 55, Boston, 02114, Massachusetts, USA

    Dean M. Donahue

  5. Neurological Associates of West LA, Wilshire Blvd, Suite 790 2811, Santa Monica, 90403, California, USA

    Sheldon E. Jordan

  6. , Graduate Program in Physical Therapy, UCSF/SFSU, Balmoral Street 2429, Union City, 94587, California, USA

    Peter I. Edgelow

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© 2013 Springer-Verlag London

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Azizzadeh, A., Nguyen, L.L., Thompson, R.W. (2013). Directions in Clinical Research on ATOS. In: Illig, K., Thompson, R., Freischlag, J., Donahue, D., Jordan, S., Edgelow, P. (eds) Thoracic Outlet Syndrome. Springer, London. https://doi.org/10.1007/978-1-4471-4366-6_89

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  • DOI: https://doi.org/10.1007/978-1-4471-4366-6_89

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  • Publisher Name: Springer, London

  • Print ISBN: 978-1-4471-4365-9

  • Online ISBN: 978-1-4471-4366-6

  • eBook Packages: MedicineMedicine (R0)

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