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Biochemistry of Zinc in Cell Division and Tissue Growth

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Zinc in Human Biology

Part of the book series: ILSI Human Nutrition Reviews ((ILSI HUMAN))

Abstract

Young rats offered a zinc-deficient diet show an abrupt reduction in growth after only a few days on the diet and before a major reduction in total body zinc content or concentration has occurred (Williams and Mills 1970). This coincides with an equally abrupt reduction in food intake to a level which, in pair-fed animals, severely restricts growth (Chesters and Quarterman 1970). However, when the intake of zinc-deficient rats is increased by gavage to that of controls offered the zinc-adequate diet ad lib, the animals fail to grow and become ill (Chesters and Quarterman 1970; Masters et al. 1983). The reduced tissue growth of a zinc-deficient rat results therefore from a zinc-responsive biochemical defect rather than from a physiological effect of loss of appetite.

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Authors
  1. J. K. Chesters
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Editors and Affiliations

  1. Rowett Research Institute, AB2 9SB, Bucksburn, Aberdeen, Scotland, UK

    Colin F. Mills MSc, PhD, CChem, FRSC, FRSE (Director of Postgraduate Studies) (Director of Postgraduate Studies)

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© 1989 Springer-Verlag Berlin Heidelberg

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Chesters, J.K. (1989). Biochemistry of Zinc in Cell Division and Tissue Growth. In: Mills, C.F. (eds) Zinc in Human Biology. ILSI Human Nutrition Reviews. Springer, London. https://doi.org/10.1007/978-1-4471-3879-2_7

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  • DOI: https://doi.org/10.1007/978-1-4471-3879-2_7

  • Publisher Name: Springer, London

  • Print ISBN: 978-1-4471-3881-5

  • Online ISBN: 978-1-4471-3879-2

  • eBook Packages: Springer Book Archive

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