Abstract
When reviewing the consequences of zinc deficiency in humans, Hambidge (1981) commented
behavioural abnormalities are prominent in severe zinc deficiency (Walravens et al. 1978) and may also occur in less severe cases of zinc depletion. Irritability, lethargy and depression are evident even at an early stage in the clinical course. Improvement in hedonic tone and motivation to engage in the environment follow rapidly after the institution of zinc therapy.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
Similar content being viewed by others
References
Caldwell DF, Oberleas D, Prasad A (1976) Psychobiological changes in zinc deficiency. In: Prasad A, Oberleas D (eds) Trace elements in human health and disease. Academic Press, New York, pp 311–325
Chafetz MD, Abshire FM, Bernard DL (1984) Zinc deficiency in adult rats alters foraging in a radial arm maze. In: Frederickson CJ, Howell GA, Kasarskis EJ (eds) The neurobiology of zinc, part B: Deficiency, toxicity and pathology. Alan R. Liss, New York, pp 109–119
Crowley DE, Hepp-Raymond HC (1966) Development of cochlear function in the ear of the infant rat. J Comp Physiol Psychol 62: 427–432
Essatara MB, Levine AS, Morley JE, McClain CJ (1984) Zinc deficiency and anorexia in rats: normal feeding patterns and stress induced feeding. Physiol Behav 32: 469–474
Golub MS, Gershwin ME, Vijayan VK (1983) Passive avoidance performance of mice fed marginally or severely zinc deficient diets during post-embryonic brain development. Physiol Behav 30: 409–413
Golub MS, Keen CL, Vijayan VK, Gershwin ME, Hurley LS (1984) Early development of brain and behaviour in mice fed a marginally zinc deficient diet. In: Frederickson CJ, Howell GA, Kasarskis EJ (eds) The neurobiology of zinc, part B: Deficiency, toxicity and pathology. Alan R. Liss, New York, pp 65–75
Gordon EF, Bond JT, Gordon RC, Denny MR (1982) Zinc deficiency and behavior: a developmental perspective. Physiol Behav 28: 893–897
Halas ES, Sandstead HH (1975) Some effects of prenatal zinc deficiency on behavior of the adult rat. Pediatr Res 9: 94–97
Halas ES, Kawamoto JC (1984) Correlated behavioral and hippocampal effects due to perinatal zinc deprivation. In: Frederickson CJ, Howell GA, Kasarskis EJ (eds) The neurobiology of zinc, part B: Deficiency, toxicity and pathology. Alan R. Liss, New York, pp 91–107
Halas ES, Reynolds GM, Sandstead HH (1977) Intra-uterine nutrition and its effects on aggression. Physiol Behav 19: 653–661
Halas ES, Heinrich MD, Sandstead HH (1979) Long term memory deficits in adult rats due to postnatal malnutrition. Physiol Behav 22: 991–997
Halas ES, Eberhard MJ, Diers MA, Sandstead HH (1983) Learning and memory impairment in adult rats due to severe zinc deficiency during lactation. Physiol Behav 30: 371–381
Halas ES, Rowe MC, Johnson OR, McKenzie JM, Sandstead HH (1976) Effects of intrauterine zinc deficiency on subsequent behavior. In: Prasad AS (ed) Proceedings of the international symposium on trace elements in human health and disease. Nutrition Foundation Monograph. Academic Press, New York, pp 327–343
Hambidge KM (1981) Zinc deficiency in man: its origins and effects. Philos Trans R Soc Lond [Biol] 294: 129–144
Lokken PM, Halas ES, Sandstead HH (1973) Influences of zinc deficiency on behavior. PSEBM 144: 680–682
Massaro TF, Mohs M, Fosmire G (1982) Effects of moderate zinc deficiency on cognitive performance in young adult rats. Physiol Behav 25: 117–121
Peters DP (1978) Effects of prenatal nutritional deficiency on affiliation and aggression in rats. Physiol Behav 20: 359–362
Rowe MC (1984) Physiological and behavioral effects of zinc deficiency in rats. MA thesis, University of North Dakota, Grand Forks
Strobel DA, Sandstead HH (1984) Social and learning changes following prenatal or postnatal zinc deprivation in rhesus monkeys. In: Frederickson CJ, Howell GA, Kasarskis EJ (eds) The neurobiology of zinc, part B: Deficiency, toxicity and pathology. Alan R.Liss, New York, pp 121–138
Walravens PA, van Doorninck WJ, Hambidge KM (1978) Metals and mental function. J Pediatr 93: 535–541
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1989 Springer-Verlag Berlin Heidelberg
About this chapter
Cite this chapter
File, S.E. (1989). Zinc and Behaviour. In: Mills, C.F. (eds) Zinc in Human Biology. ILSI Human Nutrition Reviews. Springer, London. https://doi.org/10.1007/978-1-4471-3879-2_14
Download citation
DOI: https://doi.org/10.1007/978-1-4471-3879-2_14
Publisher Name: Springer, London
Print ISBN: 978-1-4471-3881-5
Online ISBN: 978-1-4471-3879-2
eBook Packages: Springer Book Archive