Abstract
Myocardial perfusion imaging (MPI) was developed more than 30 years ago initially as a 2-dimensional (planar) technique using a potassium analog, thallium-201, which was retained within myocardial tissue in proportion to blood flow. Since then, new radiopharmaceuticals possessing the superior imaging properties of Tc-99 m have been developed and tomographic imaging (single-photon computed emission tomography; SPECT) has become the imaging standard, providing outstanding 3-dimensional localization and extent determination of perfusion abnormalities (Table 1.1). Electrocardiographic gating is now routine, providing accurate assessment of left ventricular function and enhanced recognition of soft-tissue artifacts. Attenuation correction techniques and software modifications permit contemporary SPECT imaging to provide greatly improved image quality and higher diagnostic accuracy. Traditional gamma cameras have been modified for compact use, and high efficiency detectors as well as mutli-detector technology allow for marked reduction in radiation dose and/or reduced acquisition time.
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© 2013 Springer-Verlag London
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Hendel, R.C., Hendel, R.C. (2013). SPECT. In: Heller, G., Hendel, R. (eds) Handbook of Nuclear Cardiology. Springer, London. https://doi.org/10.1007/978-1-4471-2945-5_1
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DOI: https://doi.org/10.1007/978-1-4471-2945-5_1
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