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Malignant Mesothelioma: Epidemiology

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Occupational Cancers

Abstract

Primary malignant neoplasms of the pleura and peritoneum originate from the mesothelial cells that line the respective cavities. The majority of these tumors are mesotheliomas. Mesothelioma is a relatively rare but very severe neoplasm, Exposure to asbestos (primarily on the workplace) is the main cause of mesothelioma. All types of asbestos fibers cause mesothelioma, but the potency of amphiboles is greater than that of chrysotile. The main determinant of mesothelioma risk is time since first asbestos exposure; duration and level of exposure play a minor role.

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References

  1. Acheson ED, Gardner MJ, Pippard EC, Grime LP. Mortality of two groups of women who manufactured gas masks from chrysotile and crocidolite asbestos: a 40-year follow-up. Br J Ind Med. 1982;39:344–8.

    CAS  PubMed Central  PubMed  Google Scholar 

  2. Acheson ED, Gardner MJ, Winter PD, Bennett C. Cancer in a factory using amosite asbestos. Int J Epidemiol. 1984;13:3–10.

    CAS  PubMed  Google Scholar 

  3. Agudo A, Gonzalez CA, Bleda MJ, Ramirez J, Hernandez S, Lopez F, et al. Occupation and risk of malignant pleural mesothelioma: a case-control study in Spain. Am J Ind Med. 2000;37:159–68.

    CAS  PubMed  Google Scholar 

  4. Albin M, Jakobsson K, Attewell R, Johansson L, Welinder H. Mortality and cancer morbidity in cohorts of asbestos cement workers and referents. Br J Ind Med. 1990;47:602–10.

    CAS  PubMed Central  PubMed  Google Scholar 

  5. Algranti E. Asbestos: current issues related to cancer and to uses in developing countries. Cad Saude Publica. 1998;14 Suppl 3:173–6.

    PubMed  Google Scholar 

  6. Alies-Patin AM, Valleron AJ. Mortality of workers in a French asbestos cement factory 1940–82. Br J Ind Med. 1985;42:219–25.

    CAS  PubMed Central  PubMed  Google Scholar 

  7. Amandus HE, Wheeler R. The morbidity and mortality of vermiculite miners and millers exposed to tremolite-actinolite: Part II. Mortality. Am J Ind Med. 1987;11:15–26.

    CAS  PubMed  Google Scholar 

  8. Armstrong BK, de Klerk NH, Musk AW, Hobbs MS. Mortality in miners and millers of crocidolite in Western Australia. Br J Ind Med. 1988;45:5–13.

    CAS  PubMed Central  PubMed  Google Scholar 

  9. Banaei A, Auvert B, Goldberg M, Gueguen A, Luce D, Goldberg S. Future trends in mortality of French men from mesothelioma. Occup Environ Med. 2000;57:488–94.

    CAS  PubMed Central  PubMed  Google Scholar 

  10. Bianchi C, Brollo A, Ramani L, Zuch C. Pleural plaques as risk indicators for malignant pleural mesothelioma: a necropsy-based study. Am J Ind Med. 1997;32:445–9.

    CAS  PubMed  Google Scholar 

  11. Boffetta P, Saracci R, Andersen A, Bertazzi PA, Chang-Claude J, Cherrie J, et al. Cancer mortality among man-made vitreous fiber production workers. Epidemiology. 1997;8:259–68.

    CAS  PubMed  Google Scholar 

  12. Boffetta P, Stayner LT. Pleural and peritoneal neoplasms. In: Schottenfeld D, Fraumeni JF, editors. Cancer epidemiology and prevention. 3rd ed. New York: Oxford University Press; 2006. p. 659–73.

    Google Scholar 

  13. Brooks SM, Stockwell HG, Pinkham PA, Armstrong AW, Witter DA. Sugarcane exposure and the risk of lung cancer and mesothelioma. Environ Res. 1992;58:195–203.

    CAS  PubMed  Google Scholar 

  14. Chellini E, Fornaciai G, Merler E, Paci E, Costantini AS, Silvestri S, et al. Pleural malignant mesothelioma in Tuscany, Italy (1970–1988): II. Identification of occupational exposure to asbestos. Am J Ind Med. 1992;21:577–85.

    CAS  PubMed  Google Scholar 

  15. Chen M, Tse LA, Au RK, Yu IT, Wang XR, Lao XQ, et al. Mesothelioma and lung cancer mortality: a historical cohort study among asbestosis workers in Hong Kong. Lung Cancer. 2012;76:165–70.

    PubMed  Google Scholar 

  16. Chiazze Jr L, Watkins DK, Fryar C. Historical cohort mortality study of a continuous filament fiberglass manufacturing plant. I. White men. J Occup Environ Med. 1997;39:432–41.

    PubMed  Google Scholar 

  17. Churg A, Wright JL. Persistence of natural mineral fibers in human lungs: an overview. Environ Health Perspect. 1994;102 Suppl 5:229–33.

    CAS  PubMed Central  PubMed  Google Scholar 

  18. Cicioni C, London SJ, Garabrant DH, Bernstein L, Phillips K, Peters JM. Occupational asbestos exposure and mesothelioma risk in Los Angeles County: application of an occupational hazard survey job-exposure matrix. Am J Ind Med. 1991;20:371–9.

    CAS  PubMed  Google Scholar 

  19. Cocco P, Dosemeci M. Peritoneal cancer and occupational exposure to asbestos: results from the application of a job-exposure matrix. Am J Ind Med. 1999;35:9–14.

    CAS  PubMed  Google Scholar 

  20. Crosignani P, Forastiere F, Petrelli G, Merler E, Chellini E, Pupp N, et al. Malignant mesothelioma in thermoelectric power plant workers in Italy. Am J Ind Med. 1995;27:573–6.

    CAS  PubMed  Google Scholar 

  21. Delendi M, Riboli E, Peruzzo P, Stanta G, Cocchi A, Gardiman D, et al. Comparison of diagnoses of cancers of the respiratory system on death certificates and at autopsy. IARC Sci Publ. 1991;112:55–62.

    PubMed  Google Scholar 

  22. Delgermaa V, Takahashi K, Park EK, Le GV, Hara T, Sorahan T. Global mesothelioma deaths reported to the World Health Organization between 1994 and 2008. Bull World Health Organ. 2011;89(716–24):724A–C.

    Google Scholar 

  23. Dikensoy O. Mesothelioma due to environmental exposure to erionite in Turkey. Curr Opin Pulm Med. 2008;14:322–5.

    CAS  PubMed  Google Scholar 

  24. Enterline PE, Hartley J, Henderson V. Asbestos and cancer: a cohort followed up to death. Br J Ind Med. 1987;44:396–401.

    CAS  PubMed Central  PubMed  Google Scholar 

  25. Finkelstein MM. Mortality among employees of an Ontario asbestos-cement factory. Am Rev Respir Dis. 1984;129:754–61.

    CAS  PubMed  Google Scholar 

  26. Fletcher DE. A mortality study of shipyard workers with pleural plaques. Br J Ind Med. 1972;29:142–5.

    CAS  PubMed Central  PubMed  Google Scholar 

  27. Gaafar RM, Eldin NH. Epidemic of mesothelioma in Egypt. Lung Cancer. 2005;49 Suppl 1:S17–20.

    PubMed  Google Scholar 

  28. Gardner MJ, Winter PD, Pannett B, Powell CA. Follow up study of workers manufacturing chrysotile asbestos cement products. Br J Ind Med. 1986;43:726–32.

    CAS  PubMed Central  PubMed  Google Scholar 

  29. Gennaro V, Finkelstein MM, Ceppi M, Fontana V, Montanaro F, Perrotta A, et al. Mesothelioma and lung tumors attributable to asbestos among petroleum workers. Am J Ind Med. 2000;37:275–82.

    CAS  PubMed  Google Scholar 

  30. Germani D, Belli S, Bruno C, Grignoli M, Nesti M, Pirastu R, et al. Cohort mortality study of women compensated for asbestosis in Italy. Am J Ind Med. 1999;36:129–34.

    CAS  PubMed  Google Scholar 

  31. Giaroli C, Belli S, Bruno C, Candela S, Grignoli M, Minisci S, et al. Mortality study of asbestos cement workers. Int Arch Occup Environ Health. 1994;66:7–11.

    CAS  PubMed  Google Scholar 

  32. Goldberg M, Imbernon E, Rolland P, Gilg Soit Ilg A, Savès M, de Quillacq A, et al. The French National Mesothelioma Surveillance Program. Occup Environ Med. 2006;63:390–5.

    CAS  PubMed Central  PubMed  Google Scholar 

  33. Harding AH, Darnton A, Wegerdt J, McElvenny D. Mortality among British asbestos workers undergoing regular medical examinations (1971–2005). Occup Environ Med. 2009;66:487–95.

    CAS  PubMed  Google Scholar 

  34. Harding AH, Darnton AJ. Asbestosis and mesothelioma among British asbestos workers (1971–2005). Am J Ind Med. 2010;53:1070–80.

    PubMed  Google Scholar 

  35. Harris LV, Kahwa IA. Asbestos: old foe in 21st century developing countries. Sci Total Environ. 2003;307:1–9.

    CAS  PubMed  Google Scholar 

  36. Health Effects Institute. Asbestos in public and commercial buildings. Cambridge, MA: Health Effects Institute; 1991.

    Google Scholar 

  37. Hein MJ, Stayner LT, Lehman E, Dement JM. Follow-up study of chrysotile textile workers: cohort mortality and exposure-response. Occup Environ Med. 2007;64:616–25.

    CAS  PubMed Central  PubMed  Google Scholar 

  38. Hemminki K, Li X. Time trends and occupational risk factors for pleural mesothelioma in Sweden. J Occup Environ Med. 2003;45:456–61.

    PubMed  Google Scholar 

  39. Hilt B, Andersen A, Rosenberg J, Langard S. Cancer incidence among asbestos-exposed chemical industry workers: an extended observation period. Am J Ind Med. 1991;20:261–4.

    CAS  PubMed  Google Scholar 

  40. Hodgson JT, Jones RD. Mortality of asbestos workers in England and Wales 1971–81. Br J Ind Med. 1986;43:158–64.

    CAS  PubMed Central  PubMed  Google Scholar 

  41. Howel D, Arblaster L, Swinburne L, Schweiger M, Renvoize E, Hatton P. Routes of asbestos exposure and the development of mesothelioma in an English region. Occup Environ Med. 1997;54:403–9.

    CAS  PubMed Central  PubMed  Google Scholar 

  42. Hughes JM, Weill H, Hammad YY. Mortality of workers employed in two asbestos cement manufacturing plants. Br J Ind Med. 1987;44:161–74.

    CAS  PubMed Central  PubMed  Google Scholar 

  43. Iwatsubo Y, Pairon JC, Boutin C, Menard O, Massin N, Caillaud D, et al. Pleural mesothelioma: dose-response relation at low levels of asbestos exposure in a French population-based case-control study. Am J Epidemiol. 1998;148:133–42.

    CAS  PubMed  Google Scholar 

  44. Jarvholm B, Malker H, Malker B, Ericsson J, Sallsten G. Pleural mesotheliomas and asbestos exposure in the pulp and paper industries: a new risk group identified by linkage of official registers. Am J Ind Med. 1988;13:561–7.

    CAS  PubMed  Google Scholar 

  45. Jones JS, Smith PG, Pooley FD, Berry G, Sawle GW, Madeley RJ, et al. The consequences of exposure to asbestos dust in a wartime gas-mask factory. IARC Sci Publ. 1980;30:637–53.

    PubMed  Google Scholar 

  46. Karjalainen A, Pukkala E, Kauppinen T, Partanen T. Incidence of cancer among Finnish patients with asbestos-related pulmonary or pleural fibrosis. Cancer Causes Control. 1999;10:51–7.

    CAS  PubMed  Google Scholar 

  47. Kazan-Allen L. Asbestos and mesothelioma: worldwide trends. Lung Cancer. 2005;49 Suppl 1:S3–8.

    PubMed  Google Scholar 

  48. Kolonel LN, Yoshizawa CN, Hirohata T, Myers BC. Cancer occurrence in shipyard workers exposed to asbestos in Hawaii. Cancer Res. 1985;45:3924–8.

    CAS  PubMed  Google Scholar 

  49. Koskinen K, Pukkala E, Reijula K, Karjalainen A. Incidence of cancer among the participants of the Finnish Asbestos Screening Campaign. Scand J Work Environ Health. 2003;29:64–70.

    CAS  PubMed  Google Scholar 

  50. Langseth H, Andersen A. Cancer incidence among male pulp and paper workers in Norway. Scand J Work Environ Health. 2000;26:99–105.

    CAS  PubMed  Google Scholar 

  51. La Vecchia C, Boffetta P. Role of stopping exposure and recent exposure to asbestos in the risk of mesothelioma. Eur J Cancer Prev. 2012;21:227–30.

    PubMed  Google Scholar 

  52. Lee KH, Yoon HS, Choi SJ, Kang D. Asbestos exposure and malignant mesothelioma in Korea. Asian Pac J Cancer Prev. 2009;10:707–10.

    PubMed  Google Scholar 

  53. LeMasters GK, Lockey JE, Yiin JH, Hilbert TJ, Levin LS, Rice CH. Mortality of workers occupationally exposed to refractory ceramic fibers. J Occup Environ Med. 2003;45:440–50.

    PubMed  Google Scholar 

  54. Liddell FD, McDonald AD, McDonald JC. The 1891–1920 birth cohort of Quebec chrysotile miners and millers: development from 1904 and mortality to 1992. Ann Occup Hyg. 1997;41:13–36.

    CAS  PubMed  Google Scholar 

  55. Lin S, Wang X, Yu IT, Yano E, Courtice M, Qiu H, et al. Cause-specific mortality in relation to chrysotile-asbestos exposure in a Chinese cohort. J Thorac Oncol. 2012;7:1109–14.

    PubMed  Google Scholar 

  56. Loomis D, Dement JM, Wolf SH, Richardson DB. Lung cancer mortality and fibre exposures among North Carolina asbestos textile workers. Occup Environ Med. 2009;66:535–42.

    CAS  PubMed  Google Scholar 

  57. Magnani C, Terracini B, Ivaldi C, Mancini A, Botta M. Tumor mortality and from other causes in asbestos cement workers at the Casale Montferrato plant. Med Lav. 1996;87:133–46.

    CAS  PubMed  Google Scholar 

  58. Magnani C, Ferrante D, Barone-Adesi F, Bertolotti M, Todesco A, Mirabelli D, et al. Cancer risk after cessation of asbestos exposure: a cohort study of Italian asbestos cement workers. Occup Environ Med. 2008;65:164–70.

    CAS  PubMed  Google Scholar 

  59. Malker HR, Malker BK, Blot WJ. Mesothelioma among sugar refinery workers. Lancet. 1983;2:858.

    CAS  PubMed  Google Scholar 

  60. Maltoni C, Pinto C, Valenti D, Carnuccio R, Amaducci E, Minardi F. Mesotheliomas following exposure to asbestos used in sugar refineries: report of 12 Italian cases. Med Lav. 1995;86:478–83.

    CAS  PubMed  Google Scholar 

  61. Mancuso TF, Coulter EJ. Methodology in industrial health studies. Arch Environ Health. 1963;6:210–26.

    Google Scholar 

  62. Marsh GM, Gula MJ, Youk AO, Buchanich JM, Churg A, Colby TV. Historical cohort study of US man-made vitreous fiber production workers: II. Mortality from mesothelioma. J Occup Environ Med. 2001;43:757–66.

    CAS  PubMed  Google Scholar 

  63. Mast RW, Hesterberg TW, Glass LR, McConnell EE, Anderson R, Bernstein DM. Chronic inhalation and biopersistence of refractory ceramic fiber in rats and hamsters. Environ Health Perspect. 1994;102 Suppl 5:207–9.

    CAS  PubMed Central  PubMed  Google Scholar 

  64. McDonald AD, Case BW, Churg A, Dufresne A, Gibbs GW, Sebastien P, et al. Mesothelioma in Quebec chrysotile miners and millers: epidemiology and aetiology. Ann Occup Hyg. 1997;41:707–19.

    CAS  PubMed  Google Scholar 

  65. McDonald AD, Fry JS, Woolley AJ, McDonald JC. Dust exposure and mortality in an American chrysotile asbestos friction products plant. Br J Ind Med. 1984;41:151–7.

    CAS  PubMed Central  PubMed  Google Scholar 

  66. McDonald AD, McDonald JC, Pooley FD. Mineral fibre content of lung in mesothelial tumours in North America. Ann Occup Hyg. 1982;26:417–22.

    CAS  PubMed  Google Scholar 

  67. McDonald JC, Armstrong B, Case B, Doell D, McCaughey WT, McDonald AD, et al. Mesothelioma and asbestos fiber type. Evidence from lung tissue analyses. Cancer. 1989;63:1544–7.

    CAS  PubMed  Google Scholar 

  68. Menegozzo M, Belli S, Bruno C, Canfora V, Costigliola A, Di Cintio P, et al. Mortality due to causes correlatable to asbestos in a cohort of workers in railway car construction. Med Lav. 1993;84:193–200.

    CAS  PubMed  Google Scholar 

  69. Menegozzo S, Comba P, Ferrante D, De Santis M, Gorini G, Izzo F, et al. Mortality study in an asbestos cement factory in Naples, Italy. Ann Ist Super Sanita. 2011;47:296–304.

    PubMed  Google Scholar 

  70. Mensi C, Pellegatta M, Sieno C, Consonni D, Riboldi L, Bertazzi PA. Mesothelioma of tunica vaginalis testis and asbestos exposure. BJU Int. 2012;110:533–7.

    PubMed  Google Scholar 

  71. Meurman LO, Pukkala E, Hakama M. Incidence of cancer among anthophyllite asbestos miners in Finland. Occup Environ Med. 1994;51:421–5.

    CAS  PubMed Central  PubMed  Google Scholar 

  72. Moulin JJ, Mur JM, Wild P, Perreaux JP, Pham QT. Oral cavity and laryngeal cancers among man-made mineral fiber production workers. Scand J Work Environ Health. 1986;12:27–31.

    CAS  PubMed  Google Scholar 

  73. Muscat JE, Wynder EL. Cigarette smoking, asbestos exposure, and malignant mesothelioma. Cancer Res. 1991;51:2263–7.

    CAS  PubMed  Google Scholar 

  74. Neuberger M, Kundi M. Individual asbestos exposure: smoking and mortality – a cohort study in the asbestos cement industry. Br J Ind Med. 1990;47:615–20.

    CAS  PubMed Central  PubMed  Google Scholar 

  75. Newhouse ML, Berry G, Wagner JC. Mortality of factory workers in east London 1933–80. Br J Ind Med. 1985;42:4–11.

    CAS  PubMed Central  PubMed  Google Scholar 

  76. Newhouse ML, Sullivan KR. A mortality study of workers manufacturing friction materials: 1941–86. Br J Ind Med. 1989;46:176–9.

    CAS  PubMed Central  PubMed  Google Scholar 

  77. Ohlson CG, Hogstedt C. Lung cancer among asbestos cement workers. A Swedish cohort study and a review. Br J Ind Med. 1985;42:397–402.

    CAS  PubMed Central  PubMed  Google Scholar 

  78. Ohlson CG, Klaesson B, Hogstedt C. Mortality among asbestos-exposed workers in a railroad workshop. Scand J Work Environ Health. 1984;10:283–91.

    CAS  PubMed  Google Scholar 

  79. Oksa P, Pukkala E, Karjalainen A, Ojajarvi A, Huuskonen MS. Cancer incidence and mortality among Finnish asbestos sprayers and in asbestosis and silicosis patients. Am J Ind Med. 1997;31:693–8.

    CAS  PubMed  Google Scholar 

  80. Paci E, Dini S, Buiatti E, Seniori CA, Lenzi S, Zappa M. Malignant mesothelioma in non-asbestos textile workers in Florence. Am J Ind Med. 1987;11:249–54.

    CAS  PubMed  Google Scholar 

  81. Paci E, Zappa M, Paoletti L, Buiatti E, Chellini E, Merler E, et al. Further evidence of an excess of risk of pleural malignant mesothelioma in textile workers in Prato (Italy). Br J Cancer. 1991;64:377–8.

    CAS  PubMed Central  PubMed  Google Scholar 

  82. Pedra F, Tambellini AT, Pereira Bde B, da Costa AC, de Castro HA. Mesothelioma mortality in Brazil, 1980–2003. Int J Occup Environ Health. 2008;14:170–5.

    PubMed  Google Scholar 

  83. Pan XL, Day HW, Wang W, Beckett LA, Schenker MB. Residential proximity to naturally occurring asbestos and mesothelioma risk in California. Am J Respir Crit Care Med. 2005;172:1019–25.

    PubMed Central  PubMed  Google Scholar 

  84. Peto J, Doll R, Hermon C, Binns W, Clayton R, Goffe T. Relationship of mortality to measures of environmental asbestos pollution in an asbestos textile factory. Ann Occup Hyg. 1985;29:305–55.

    CAS  PubMed  Google Scholar 

  85. Peto J, Hodgson JT, Matthews FE, Jones JR. Continuing increase in mesothelioma mortality in Britain. Lancet. 1995;345:535–9.

    CAS  PubMed  Google Scholar 

  86. Piolatto G, Negri E, La Vecchia C, Pira E, Decarli A, Peto J. An update of cancer mortality among chrysotile asbestos miners in Balangero, northern Italy. Br J Ind Med. 1990;47:810–4.

    CAS  PubMed Central  PubMed  Google Scholar 

  87. Pira E, Pelucchi C, Buffoni L, Palmas A, Turbiglio M, Negri E, et al. Cancer mortality in a cohort of asbestos textile workers. Br J Cancer. 2005;92:580–6.

    CAS  PubMed Central  PubMed  Google Scholar 

  88. Pira E, Pelucchi C, Piolatto PG, Negri E, Bilei T, La Vecchia C. Mortality from cancer and other causes in the Balangero cohort of chrysotile asbestos miners. Occup Environ Med. 2009;66:805–9.

    CAS  PubMed  Google Scholar 

  89. Pira E, Pelucchi C, Piolatto PG, Negri E, Discalzi G, La Vecchia C. First and subsequent asbestos exposures in relation to mesothelioma and lung cancer mortality. Br J Cancer. 2007;97:1300–4.

    CAS  PubMed Central  PubMed  Google Scholar 

  90. Price B. Industrial-grade talc exposure and the risk of mesothelioma. Crit Rev Toxicol. 2010;40:513–30.

    CAS  PubMed  Google Scholar 

  91. Puntoni R, Merlo F, Borsa L, Reggiardo G, Garrone E, Ceppi M. A historical cohort mortality study among shipyard workers in Genoa, Italy. Am J Ind Med. 2001;40:363–70.

    CAS  PubMed  Google Scholar 

  92. Raffn E, Lynge E, Juel K, Korsgaard B. Incidence of cancer and mortality among employees in the asbestos cement industry in Denmark. Br J Ind Med. 1989;46:90–6.

    CAS  PubMed Central  PubMed  Google Scholar 

  93. Rake C, Gilham C, Hatch J, Darnton A, Hodgson J, Peto J. Occupational, domestic and environmental mesothelioma risks in the British population: a case-control study. Br J Cancer. 2009;100:1175–83.

    CAS  PubMed Central  PubMed  Google Scholar 

  94. Rees D, Myers JE, Goodman K, Fourie E, Blignaut C, Chapman R, et al. Case-control study of mesothelioma in South Africa. Am J Ind Med. 1999;35:213–22.

    CAS  PubMed  Google Scholar 

  95. Rodelsperger K, Jockel KH, Pohlabeln H, Romer W, Woitowitz HJ. Asbestos and man-made vitreous fibers as risk factors for diffuse malignant mesothelioma: results from a German hospital-based case-control study. Am J Ind Med. 2001;39:262–75.

    CAS  PubMed  Google Scholar 

  96. Rolland P, Gramond C, Lacourt A, Astoul P, Chamming’s S, Ducamp S, et al. Occupations and industries in France at high risk for pleural mesothelioma: A population-based case-control study (1998–2002). Am J Ind Med. 2010;53:1207–19.

    Google Scholar 

  97. Rossiter CE, Coles RM. HM Dockyard, Devonport: 1947 mortality study. IARC Sci Publ. 1980;30:713–21.

    PubMed  Google Scholar 

  98. Sanden A, Jarvholm B, Larsson S, Thiringer G. The risk of lung cancer and mesothelioma after cessation of asbestos exposure: a prospective cohort study of shipyard workers. Eur Respir J. 1992;5:281–5.

    CAS  PubMed  Google Scholar 

  99. Segura O, Burdorf A, Looman C. Update of predictions of mortality from pleural mesothelioma in the Netherlands. Occup Environ Med. 2003;60:50–5.

    CAS  PubMed Central  PubMed  Google Scholar 

  100. Seidman H, Selikoff IJ, Gelb SK. Mortality experience of amosite asbestos factory workers: dose-response relationships 5 to 40 years after onset of short-term work exposure. Am J Ind Med. 1986;10:479–514.

    CAS  PubMed  Google Scholar 

  101. Selikoff IJ, Churg J, Hammond EC. Asbestos exposure and neoplasia. JAMA. 1964;188:22–6.

    CAS  PubMed  Google Scholar 

  102. Selikoff IJ, Seidman H. Asbestos-associated deaths among insulation workers in the United States and Canada, 1967–1987. Ann N Y Acad Sci. 1991;643:1–14.

    CAS  PubMed  Google Scholar 

  103. Siemiatycki J, Boffetta P. Invited commentary: Is it possible to investigate the quantitative relation between asbestos and mesothelioma in a community-based study? Am J Epidemiol. 1998;148:143–7.

    CAS  PubMed  Google Scholar 

  104. Sinks T, Goodman M, Kolonel L, Anderson B. A case-control study of mesothelioma and exposure to biogenic silica fibers. Am J Epidemiol. 1992;136:1015.

    Google Scholar 

  105. Sluis-Cremer GK, Liddell FD, Logan WP, Bezuidenhout BN. The mortality of amphibole miners in South Africa, 1946–80. Br J Ind Med. 1992;49:566–75.

    CAS  PubMed Central  PubMed  Google Scholar 

  106. Smailyte G, Kurtinaitis J, Andersen A. Cancer mortality and morbidity among Lithuanian asbestos-cement producing workers. Scand J Work Environ Health. 2004;30:64–70.

    PubMed  Google Scholar 

  107. Stayner LT, Dankovic DA, Lemen RA. Occupational exposure to chrysotile asbestos and cancer risk: a review of the amphibole hypothesis. Am J Public Health. 1996;86:179–86.

    CAS  PubMed Central  PubMed  Google Scholar 

  108. Subhannachart P, Dumavibhat N, Siriruttanapruk S. Asbestos-related diseases in Thailand and review literature. J Med Assoc Thai. 2012;95 Suppl 8:S71–6.

    PubMed  Google Scholar 

  109. Sullivan PA. Vermiculite, respiratory disease, and asbestos exposure in Libby, Montana: update of a cohort mortality study. Environ Health Perspect. 2007;115:579–85.

    PubMed Central  PubMed  Google Scholar 

  110. Svenes KB, Borgersen A, Haaversen O, Holten K. Parietal pleural plaques: a comparison between autopsy and X-ray findings. Eur J Respir Dis. 1986;69:10–5.

    CAS  PubMed  Google Scholar 

  111. Szeszenia-Dabrowska N, Urszula W, Szymczak W, Strzelecka A. Mortality study of workers compensated for asbestosis in Poland, 1970–1997. Int J Occup Med Environ Health. 2002;15:267–78.

    PubMed  Google Scholar 

  112. Szeszenia-Dabrowska N, Wilczynska U, Szymczak W. Risk of cancer in women occupationally exposed to asbestos dust. Med Pr. 1986;37:243–9.

    CAS  PubMed  Google Scholar 

  113. Szeszenia-Dabrowska N, Wilczynska U, Szymczak W. Cancer risk in asbestos-cement industry workers in Poland. Med Pr. 1997;48:473–83.

    CAS  PubMed  Google Scholar 

  114. Talcott JA, Thurber WA, Kantor AF, Gaensler EA, Danahy JF, Antman KH, et al. Asbestos-associated diseases in a cohort of cigarette-filter workers. N Engl J Med. 1989;321:1220–3.

    CAS  PubMed  Google Scholar 

  115. Thomas HF, Benjamin IT, Elwood PC, Sweetnam PM. Further follow-up study of workers from an asbestos cement factory. Br J Ind Med. 1982;39:273–6.

    CAS  PubMed Central  PubMed  Google Scholar 

  116. Thomason R, Schlegel W, Lucca M, Cummings S, Lee S. Primary malignant mesothelioma of the pericardium. Case report and literature review. Tex Heart Inst J. 1994;21:170–4.

    CAS  PubMed Central  PubMed  Google Scholar 

  117. Tomioka K, Natori Y, Kumagai S, Kurumatani N. An updated historical cohort mortality study of workers exposed to asbestos in a refitting shipyard, 1947–2007. Int Arch Occup Environ Health. 2011;84:959–67.

    PubMed  Google Scholar 

  118. Tsai SP, Waddell LC, Gilstrap EL, Ransdell JD, Ross CE. Mortality among maintenance employees potentially exposed to asbestos in a refinery and petrochemical plant. Am J Ind Med. 1996;29:89–98.

    CAS  PubMed  Google Scholar 

  119. Tulchinsky TH, Ginsberg GM, Iscovich J, Shihab S, Fischbein A, Richter ED. Cancer in ex-asbestos cement workers in Israel, 1953–1992. Am J Ind Med. 1999;35:1–8.

    CAS  PubMed  Google Scholar 

  120. UICC. Report and recommendations of the working group on asbestos and cancer: convened under the auspices of the geographical pathology committee of the International Union against Cancer (U.I.C.C.). Br J Ind Med. 1965;22:165–71.

    Google Scholar 

  121. Ulvestad B, Kjaerheim K, Martinsen JI, Damberg G, Wannag A, Mowe G, et al. Cancer incidence among workers in the asbestos-cement producing industry in Norway. Scand J Work Environ Health. 2002;28:411–7.

    PubMed  Google Scholar 

  122. Wagner JC, Sleggs CA, Marchand P. Diffuse pleural mesothelioma and asbestos exposure in the North Western Cape Province. Br J Ind Med. 1960;17:260–71.

    CAS  PubMed Central  PubMed  Google Scholar 

  123. Watkins DK, Chiazze Jr L, Fryar C. Historical cohort mortality study of a continuous filament fiberglass manufacturing plant. II. Women and minorities. J Occup Environ Med. 1997;39:548–55.

    CAS  PubMed  Google Scholar 

  124. Weiss W. Asbestos-related pleural plaques and lung cancer. Chest. 1993;103:1854–9.

    CAS  PubMed  Google Scholar 

  125. Woitowitz HJ, Lange HJ, Beierl L, Rathgeb M, Schmidt K, Ulm K, et al. Mortality rates in the Federal Republic of Germany following previous occupational exposure to asbestos dust. Int Arch Occup Environ Health. 1986;57:161–71.

    CAS  PubMed  Google Scholar 

  126. Zhu H, Wang Z. Cancer epidemiology investigation for workers exposed to asbestos. In: The Ministry of Public Health of China, editor. National epidemiological study on 8 occupational cancers. Beijing: The Ministry of Public Health of China; 1996. p. 1–121.

    Google Scholar 

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Boffetta, P. (2014). Malignant Mesothelioma: Epidemiology. In: Anttila, S., Boffetta, P. (eds) Occupational Cancers. Springer, London. https://doi.org/10.1007/978-1-4471-2825-0_13

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