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Klinefelter’s Syndrome

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Atlas on the Human Testis

Abstract

Klinefelter’s syndrome is characterized by the presence of an abnormal number of X chromosomes and primary testicular insufficiency. Testicular lesions involve both the seminiferous tubules and testicular interstitium and are (a) atrophy of the seminiferous tubules that, through a hyalinization process, may lead to the complete disappearance of the tubules, with only ghost tubules remaining and (b) an apparent increase in the number of Leydig cells, which form characteristic nodules that tend to coalesce and delete the testicular structure.

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Authors and Affiliations

  1. Department of Pathology, University Hospital La Paz, Madrid, Spain

    Manuel Nistal M.D., Ph.D. & Pilar González-Peramato M.D., Ph.D.

  2. Department of Anatomy, Histology, and Neuroscience, University Autonoma of Madrid, Madrid, Spain

    Manuel Nistal M.D., Ph.D.

  3. Department of Pathology, University Autonoma of Madrid, Madrid, Spain

    Pilar González-Peramato M.D., Ph.D.

Authors
  1. Manuel Nistal M.D., Ph.D.
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  2. Pilar González-Peramato M.D., Ph.D.
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Correspondence to Manuel Nistal M.D., Ph.D. .

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Editors and Affiliations

  1. , Department of Histology and Embryology, University of Zagreb, Šalata 3, Zagreb, HR-10000, Croatia

    Davor Ježek

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Nistal, M., González-Peramato, P. (2013). Klinefelter’s Syndrome. In: Ježek, D. (eds) Atlas on the Human Testis. Springer, London. https://doi.org/10.1007/978-1-4471-2763-5_11

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  • DOI: https://doi.org/10.1007/978-1-4471-2763-5_11

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  • Publisher Name: Springer, London

  • Print ISBN: 978-1-4471-2762-8

  • Online ISBN: 978-1-4471-2763-5

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