Abstract
Twenty days after receiving an autograft for non-Hodgkin’s lymphoma, a 46-year-old male has a platelet count of 13 × 109/l. He requires drainage of pleural effusion; hospital transfusion guideline mandates that the platelet count should be at least 50 × 109/l before the procedure. He is transfused a unit of pooled, ABO-matched platelets; an hour after the transfusion, the platelet count is 21 × 109/l.
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Notes
- 1.
National health service Blood and Transplant produces platelets units from whole blood donations of four donors. Thus, an average content of a platelet “pool” is 2.2 x 10e11.
References
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Slichter SJ et al. Leukocyte reduction and ultraviolet B irradiation of platelets to prevent alloimmunization and refractoriness to platelet transfusions. The Trial to Reduce Alloimmunization to Platelets study group. N Engl J Med. 1997;337:1861–9.
Further Reading
Hod E, Schwartz J. Platelet transfusion refractoriness. Br J Haematol. 2008;142:348–60.
Rubinstein P. Platelet transfusions to HLA-immunized recipients: how to be or not to be matched. Transfusion. 2010;50:2292–4.
Vassallo R, Murphy S. Preservation and clinical use of platelets. In: Lichtman MA et al., editors. Williams haematology. 7th ed. New York: McGraw-Hill; 2005. p. 2175–89.
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© 2012 Springer-Verlag London Limited
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Mijovic, A. (2012). The Matchmaker. In: Transfusion Medicine. Springer, London. https://doi.org/10.1007/978-1-4471-2182-4_17
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DOI: https://doi.org/10.1007/978-1-4471-2182-4_17
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