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Ring-Cleavage Dioxygenases

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Pseudomonas

Abstract

Pseudomonads have an exceptional ability to utilize aromatic compounds as sole source of energy and carbon. This capability is critical to maintaining the global carbon cycle. Aromatic compounds are planar, fully conjugated, ring-shaped molecules possessing (4n + 2)π electrons where n is a nonnegative integer (Hückel’s rule)93. Formed by a variety of biogeochemical processes, these compounds are widely distributed in nature, and range in size from low-molecular-mass compounds, such as phenols, to biopolymers, such as lignin. Indeed, lignin is the second most abundant polymer in nature after cellulose2. Aromatic compounds are exceptionally stable due to the delocalization of their π orbitals (resonance structure). This property has contributed to the wide spread production and usage of natural and non-natural aromatic compounds for a variety of industrial applications, as well as the distribution of stable, nonnatural compounds in the environment.

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  1. Departments of Microbiology and Biochemistry, University of British Columbia, Vancouver, Canada

    Frédéric H. Vaillancourt & Lindsay D. Eltis

  2. Markey Center for Structural Biology, Department of Biological Sciences, Purdue University, West Lafayette, Indiana, USA

    Jeffrey T. Bolin

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Vaillancourt, F.H., Bolin, J.T., Eltis, L.D. (2004). Ring-Cleavage Dioxygenases. In: Ramos, JL. (eds) Pseudomonas. Springer, Boston, MA. https://doi.org/10.1007/978-1-4419-9088-4_13

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