Skip to main content

Keynote Lecture to the WCCBME Biomedical Engineering’s Many Foundations

  • Conference paper
Frontiers in Biomedical Engineering

Abstract

It is my great pleasure to welcome you all to this World Congress. We come from all over the world to share our knowledge of the field we love, exchange our views, and promote friendship. Our field is huge. If I were allowed to choose one word to characterize our field, I would say that it is diverse: diverse with a unified purpose. Our unified purpose is to understand the health and disease of man and animals, and to do what we can for the benefit of human beings. Together, we bring the entire field of engineering to serve medical research and health science. We use the engineering approach. We value scientific and humanitarian understanding. We believe that true understanding is the foundation of everything that is worthwhile. We use pure science. We use engineering science. We use technology. We develop new and old materials, tools, mathematics, computing techniques, informatics, laboratories and clinical trials. We hope to add clarity and definitiveness to our understanding of diseases, clinical approaches, medicine, surgery, physical exercise, nutrition, healing, and the sense of well-being. Knowledge has no boundaries; it cannot be compartmentalized. Hence, for us, diversity is normal; it is the key.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 169.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 219.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Similar content being viewed by others

References

  1. B. Meyrick and L. Reid, The effect of continued hypoxia on rat pulmonary arterial circulation: An ultrastructural study, Lab. Invest. 38 (1978), 188–200.

    Google Scholar 

  2. S.S. Sobin, H.M. Tremer, J.D. Hardy and H.R Chiodi, Changes in arteriole in acute and chronic hypoxic pulmonary hypertension and recovery in rat, J. Appl. Physiol. 55 (1983), 1445–1455.

    Google Scholar 

  3. U.S. von Euler and G. Liljestrand, Observations on the pulmonary arterial blood pressure in the cat, Acta Physiol Scand 12 (1946), 301–320.

    Article  Google Scholar 

  4. J.B. West, High life: A history of high-altitude physiology and medicine, Oxford University Press, New York, 1998.

    Book  Google Scholar 

  5. Y.C. Fung and S.Q. Liu, Changes of zero-stress state of rat pulmonary arteries in hypoxic hypertension, J App. Physio. 70 (1991), 2455–2470.

    Article  Google Scholar 

  6. Y.C. Fung, Biodynamics: Circulation, Springer-Verlag, New York, 1984.

    Google Scholar 

  7. W. Huang, D. Delgado-West, J.T. Wu and Y.C. Fung, Tissue remodeling of rat pulmonary artery in hypoxic breathing: II. Course of change of mechanical properties, Ann. Biomed. Eng. 29 (2001) 552–562.

    Article  Google Scholar 

  8. W. Huang, Z. Shen, N.E. Huang and Y.C. Fung, Engineering analysis of biological variables: An example of blood pressure over 1 day, Proc. Natl Acad. Sci. USA, 95 (1998), 4816–4821.

    Article  Google Scholar 

  9. W. Huang, Z. Shen, N.E. Huang and Y.C. Fung, Use of intrinsic modes in biology: Examples of indicial response of pulmonary blood pressure to step hypoxia, Proc. Natl Acad Sci USA, 95 (1998), 12766–12771.

    Article  Google Scholar 

  10. W. Huang, Z. Shen, N.E. Huang and Y.C. Fung, Nonlinear Indicial Response of Complex Nonstationary Oscillations as Pulmonary Hypertension Responding to Step Hypoxia, Proc Natl Acad. Sc. USA, 96 (1999), 1834–1839.

    Article  Google Scholar 

  11. W. Huang, Y.P. Sher, D. Delgado-West, J.T. Wu, K. Peck and Y.C. Fung, Tissue remodeling of ratpulmonary artery in hypoxic breathing: I. Changes of morphology, zero-stress state and gene expression, Ann Biomed Eng 2000 (in review)

    Google Scholar 

  12. Z. L., Jiang, G. S. Kassab and Y. C. Fung, Diameter-Defined Strahler system and connectivity matrix of the pulmonary arterial tree, J Appl Physiol 76 (1994), 882–892.

    Google Scholar 

  13. W. Huang, Y.P. Sher, K. Peck, and Y.C. Fung, Correlations of gene expression with physiological functions: examples of pulmonary blood vessels rhealogy, hypoxic hypertension, and tissue remodeling, Biorhealogy, 38 (2001), 75–87.

    Google Scholar 

  14. W. Huang, Y.P. Sher, K. Peck and Y.C. Fung, Matching gene activity with physiological functions, Proc Nat Acad Sci, U.S. 99 (2002), 2603–2608.

    Article  Google Scholar 

  15. G.S. Kassab, C.A. Rider, N.A. Tang, and Y.C. Fung, Morphometry of pig coronary arterial trees, Am J Physiol 265 (1993), H350–H365.

    Google Scholar 

  16. S.F. Altschul, T. L. Madden, A. A. Schaffer, J. Zhang, Z. Zhang, W. Miller and D. J. Lipman, Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. Nucleic Acids Res. 25 (1997), 3389–402.

    Article  Google Scholar 

  17. D.A. Benson, M.S. Boguski, D.J. Lipman and J. Ostell, GenBank, Nucleic Acids Res. 25 (1977), 1–6.

    Article  Google Scholar 

  18. JJ.W. Chen, R. Wu, P.C. Yang, J.Y. Huang, Y.P. Sher, M.H. Han, W.C. Kao, P.J. Lee, T.F. Chiu, F. Chang, Y.W. Chu, C.W. Wu and K. Peck, Profiling expression patterns and isolating differentially expressed genes by cDNA microarray system with colorimetry detection, Genomics 51 (1998), 313–324.

    Article  Google Scholar 

  19. G.D. Schuler, M.S. Boguski, E.A. Stewart, L.D. Stein, G. Gyapay, K. Rice, R.E. White and P. Rodrigues- Tome, A. Aggarwal, E. Barjorek, et al., A gene map of the human genome. Science 274 (1996), 540–546.

    Article  Google Scholar 

  20. G.G. Lennon, C. Auffray, M. Polymeropoulos and M.B. Soares. The I.M.A.G.E. Consortium: An Integrated Molecular Analysis of Genomes and their Expression, Genomics 33 (1996), 151–152.

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2003 Springer Science+Business Media New York

About this paper

Cite this paper

Fung, B.YC. (2003). Keynote Lecture to the WCCBME Biomedical Engineering’s Many Foundations. In: Hwang, N.H.C., Woo, S.LY. (eds) Frontiers in Biomedical Engineering. Topics in Biomedical Engineering International Book Series. Springer, Boston, MA. https://doi.org/10.1007/978-1-4419-8967-3_1

Download citation

  • DOI: https://doi.org/10.1007/978-1-4419-8967-3_1

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-4739-2

  • Online ISBN: 978-1-4419-8967-3

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics