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Cartilage Matrix Assessment Using dGEMRIC

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Cartilage Imaging

Abstract

The functional integrity of cartilage is inextricably linked to the composition and architecture of the macromolecular network of cartilage. There has been much recent attention to developing nondestructive methods for imaging cartilage macromolecules. Over the next decade these should become sufficiently robust to serve as an important adjunct to the currently used destructive methods of microscopic and bulk biochemical analyses.

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Acknowledgments

The authors deeply appreciate the dozens of collaborators, students, post-docs, and staff with whom we have worked over the last decades in developing and using the methods described here. We also deeply appreciate the essential support provided by numerous funding agencies, including: Proctor and Gamble Exploratory Research award, NIH-NIAMS, Arthritis Foundation, Pfizer, Orthopedic Research and Education Foundation (OREF), and Pharmacia. Finally, we thank the publisher and editors of the Journal of Orthopaedic Research who generously allowed us to use much of the text from an earlier review [1] in the preparation of this chapter.

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Authors and Affiliations

  1. Department of Radiology, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Boston, MA, 02215, USA

    Deborah Burstein

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  1. Martha L. Gray
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Correspondence to Deborah Burstein .

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Editors and Affiliations

  1. Dept. Radiology, University of California, San Francisco, 400 Parnassus Ave., A-367, San Francisco, 94143-0628, California, USA

    Thomas M. Link

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Gray, M.L., Burstein, D. (2011). Cartilage Matrix Assessment Using dGEMRIC. In: Link, T. (eds) Cartilage Imaging. Springer, New York, NY. https://doi.org/10.1007/978-1-4419-8438-8_14

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  • DOI: https://doi.org/10.1007/978-1-4419-8438-8_14

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