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Handbook of Practical Immunohistochemistry

Abstract

This chapter provides a practical overview of ­frequently used markers in the diagnosis and differential diagnosis of both common and rare renal neoplasms, with a specific focus on renal epithelial tumors and their mimickers. The chapter contains 52 questions; each question is addressed with a table, concise note and representative pictures if applicable. In addition to the literature review, the authors have included their own experience and tested numerous antibodies reported in the literature. The most effective diagnostic panels of antibodies have been recommended for many entities, such as PAX8, RCCMa, and KIM-1 being suggested as the best diagnostic panel for identifying clear cell renal cell carcinoma. Furthermore, immunophenotypes of normal renal tissues have been described, which tends to be neglected in literature. Prognostic markers for renal cell carcinoma have been briefly mentioned.

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  1. Department of Pathology and Laboratory Medicine, Geisinger Medical Center, 100 N. Academy Ave, Danville, PA, 17822, USA

    Fan Lin

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  2. Ximing J. Yang
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  1. , Pathology and Laboratory Medicine, Geisinger Health System, 100 N. Academy Avenue, Danville, 17822, Pennsylvania, USA

    Fan Lin

  2. , Pathology and Laboratory Medicine, Geisinger Medical Center, 100 N. Academy Avenue, Danville, 17822, Pennsylvania, USA

    Jeffrey Prichard

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Lin, F., Yang, X.J. (2011). Kidney. In: Lin, F., Prichard, J. (eds) Handbook of Practical Immunohistochemistry. Springer, New York, NY. https://doi.org/10.1007/978-1-4419-8062-5_20

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