Abstract
• Melanocytic lesions with some, but not all, of the features of melanoma (Table 3.1)
• Dysplastic nevus (Clark’s nevus or atypical nevus)
– Definition: pigmented lesion with some clinical and histologic features of melanoma but with still undetermined biologic behavior
– Sporadic lesions seen in 1–15% of Caucasian Americans (most series)
– Relative risk for developing melanoma about 7% (cumulative lifetime risk about 6%)
– Type D2 dysplastic nevus syndrome (dysplastic nevi on a person with multiple relatives with melanoma and dysplastic nevi) – 20,000–30,000 such patients in USA, cumulative lifetime risk of melanoma approaches 100%
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Smoller, B.R., Hiatt, K.M. (2011). Histologic Mimics of Malignant Melanoma. In: Epidermal Cell Tumors: The Basics. Springer, Boston, MA. https://doi.org/10.1007/978-1-4419-7704-5_3
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DOI: https://doi.org/10.1007/978-1-4419-7704-5_3
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